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Molecules 2001, 6(12), 959-963; doi:10.3390/61200959
Article

An Improved Synthesis of 5-(2,6-Dichlorophenyl)-2-(phenylthio)-6H-pyrimido[1,6-b]pyridazin-6-one (a VX-745 analog)

1, 1,*  and 2
Received: 22 October 2001; in revised form: 30 October 2001 / Accepted: 30 October 2001 / Published: 30 November 2001
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Abstract: An improved procedure for the synthesis an analog of the p38 inhibitor compound VX- 745 is reported.
Keywords: nucleophilic substitution; DMF-acetal heterocyclization nucleophilic substitution; DMF-acetal heterocyclization
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Treu, M.; Jordis, U.; Lee, V.J. An Improved Synthesis of 5-(2,6-Dichlorophenyl)-2-(phenylthio)-6H-pyrimido[1,6-b]pyridazin-6-one (a VX-745 analog). Molecules 2001, 6, 959-963.

AMA Style

Treu M, Jordis U, Lee VJ. An Improved Synthesis of 5-(2,6-Dichlorophenyl)-2-(phenylthio)-6H-pyrimido[1,6-b]pyridazin-6-one (a VX-745 analog). Molecules. 2001; 6(12):959-963.

Chicago/Turabian Style

Treu, Matthias; Jordis, Ulrich; Lee, Ving J. 2001. "An Improved Synthesis of 5-(2,6-Dichlorophenyl)-2-(phenylthio)-6H-pyrimido[1,6-b]pyridazin-6-one (a VX-745 analog)." Molecules 6, no. 12: 959-963.


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