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Molecules 2000, 5(3), 537-538; doi:10.3390/50300537
Abstract

Solid-Phase Organic Chemistry: Synthesis of 2β-(Heterocyclylthiomethyl)Penam Derivatives on Solid Support

 and *
Instituto de Química Orgánica de Síntesis (CONICET - UNR), Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Casilla de Correo 991, 2000 – Rosario, Argentina
* Author to whom correspondence should be addressed.
Published: 22 March 2000
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Abstract

The synthesis of 2β-(heterocyclylthiomethyl)penam derivatives on solid support has been developed. Compounds are obtained in good to high yields (based on loading of the original resin). The key step is the solid-phase double rearrangement of the corresponding penicillin sulfoxide.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Delpiccolo, C.M.; Mata, E.G. Solid-Phase Organic Chemistry: Synthesis of 2β-(Heterocyclylthiomethyl)Penam Derivatives on Solid Support. Molecules 2000, 5, 537-538.

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