Solid-Phase Organic Chemistry: Synthesis of 2β-(Heterocyclylthiomethyl)Penam Derivatives on Solid Support

doi:10.3390/50300537

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Molecules 2000, 5(3), 537-538; doi:10.3390/50300537

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Solid-Phase Organic Chemistry: Synthesis of 2β-(Heterocyclylthiomethyl)Penam Derivatives on Solid Support

Carina M.L. Delpiccolo and Ernesto G. Mata*

Instituto de Química Orgánica de Síntesis (CONICET - UNR), Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Casilla de Correo 991, 2000 – Rosario, Argentina

* Author to whom correspondence should be addressed.

Published: 22 March 2000

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Abstract: The synthesis of 2β-(heterocyclylthiomethyl)penam derivatives on solid support has been developed. Compounds are obtained in good to high yields (based on loading of the original resin). The key step is the solid-phase double rearrangement of the corresponding penicillin sulfoxide.

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MDPI and ACS Style

Delpiccolo, C.M.; Mata, E.G. Solid-Phase Organic Chemistry: Synthesis of 2β-(Heterocyclylthiomethyl)Penam Derivatives on Solid Support. Molecules 2000, 5, 537-538.

AMA Style

Delpiccolo CM, Mata EG. Solid-Phase Organic Chemistry: Synthesis of 2β-(Heterocyclylthiomethyl)Penam Derivatives on Solid Support. Molecules. 2000; 5(3):537-538.

Chicago/Turabian Style

Delpiccolo, Carina M.; Mata, Ernesto G. 2000. "Solid-Phase Organic Chemistry: Synthesis of 2β-(Heterocyclylthiomethyl)Penam Derivatives on Solid Support." Molecules 5, no. 3: 537-538.

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