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Molecules 2000, 5(3), 428-430; doi:10.3390/50300428

Synthesis and In Vitro Antigungal Properties of 4-Aryl-4-Narylamine-1-butenes and Related Compounds

Quím. Org. Fina, Fac. Quím., Univ. Ind. de Santander, A.A. 678, Bucaramanga, Colombia
Farmacognosia, Fac.Cs. Bioq. y Farm., Univ.Nac de Rosario, Suipacha 531, (2000)-Rosario, Argentina
Quím.Gral, Fac. de Quím., Bioq. y Farm., Chacabuco y Pedernera, (5700)-San Luis, Argentina
Author to whom correspondence should be addressed.
Published: 22 March 2000
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A new series of 4-aryl and 4-alkyl-4-N-arylamine-1-butenes (homoallylamines) were synthesized and some of them transformed to 4-aryl or alkylquinolines. All of them showed strong antifungal activities against human pathogenic fungi in vitro, being Epidermophyton floccosum the most susceptible species. View Full-Text

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This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Kouznetsov, V.; Urbina, J.; Palma, A.; López, S.; Devia, C.; Enriz, R.; Zacchino, S. Synthesis and In Vitro Antigungal Properties of 4-Aryl-4-Narylamine-1-butenes and Related Compounds. Molecules 2000, 5, 428-430.

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