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Molecules 2000, 5(2), 153-161; doi:10.3390/50200153
Article

Synthesis of 4-O-Methylcedrusin. Selective Protection of Catechols with Diphenyl Carbonate

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Received: 1 November 1999; Accepted: 19 January 2000 / Published: 18 February 2000
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Abstract: 4-O-Methylcedrusin, a minor component in ‘sangre de drago’, has been synthesized using a strategy of successive protection and deprotection reactions under very mild conditions. The key step of this synthesis is a selective protection of a catechol group as a cyclic carbonate in the presence of an isolated phenol group.
Keywords: Carbonates; lignans; phenolics; protecting groups; natural products Carbonates; lignans; phenolics; protecting groups; natural products
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Van Dyck, S.M.O.; Lemière, G.L.F.; Jonckers, T.H.M.; Dommisse, R. Synthesis of 4-O-Methylcedrusin. Selective Protection of Catechols with Diphenyl Carbonate. Molecules 2000, 5, 153-161.

AMA Style

Van Dyck SMO, Lemière GLF, Jonckers THM, Dommisse R. Synthesis of 4-O-Methylcedrusin. Selective Protection of Catechols with Diphenyl Carbonate. Molecules. 2000; 5(2):153-161.

Chicago/Turabian Style

Van Dyck, Stefaan M.O.; Lemière, Guy L.F.; Jonckers, Tim H.M.; Dommisse, Roger. 2000. "Synthesis of 4-O-Methylcedrusin. Selective Protection of Catechols with Diphenyl Carbonate." Molecules 5, no. 2: 153-161.



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