Molecules 2000, 5(2), 153-161; doi:10.3390/50200153
Article

Synthesis of 4-O-Methylcedrusin. Selective Protection of Catechols with Diphenyl Carbonate

Stefaan M. O. Van Dyck, Guy L. F. Lemière* email, Tim H. M. Jonckers and Roger Dommisse
Department of Chemistry, Laboratory of Natural Product Synthesis for Chemotherapy, University of Antwerp (RUCA), Groenenborgerlaan 171, 2020 Antwerpen, Belgium
* Author to whom correspondence should be addressed.
Received: 1 November 1999 / Accepted: 19 January 2000 / Published: 18 February 2000
PDF Full-text Download PDF Full-Text [51 KB, uploaded 6 October 2008 16:09 CEST]
Abstract: 4-O-Methylcedrusin, a minor component in ‘sangre de drago’, has been synthesized using a strategy of successive protection and deprotection reactions under very mild conditions. The key step of this synthesis is a selective protection of a catechol group as a cyclic carbonate in the presence of an isolated phenol group.
Keywords: Carbonates; lignans; phenolics; protecting groups; natural products

Article Statistics

Click here to load and display the download statistics.

Cite This Article

MDPI and ACS Style

Van Dyck, S.M.O.; Lemière, G.L.F.; Jonckers, T.H.M.; Dommisse, R. Synthesis of 4-O-Methylcedrusin. Selective Protection of Catechols with Diphenyl Carbonate. Molecules 2000, 5, 153-161.

AMA Style

Van Dyck SMO, Lemière GLF, Jonckers THM, Dommisse R. Synthesis of 4-O-Methylcedrusin. Selective Protection of Catechols with Diphenyl Carbonate. Molecules. 2000; 5(2):153-161.

Chicago/Turabian Style

Van Dyck, Stefaan M.O.; Lemière, Guy L.F.; Jonckers, Tim H.M.; Dommisse, Roger. 2000. "Synthesis of 4-O-Methylcedrusin. Selective Protection of Catechols with Diphenyl Carbonate." Molecules 5, no. 2: 153-161.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert