Molecules 2000, 5(2), 153-161; doi:10.3390/50200153
Article

Synthesis of 4-O-Methylcedrusin. Selective Protection of Catechols with Diphenyl Carbonate

Department of Chemistry, Laboratory of Natural Product Synthesis for Chemotherapy, University of Antwerp (RUCA), Groenenborgerlaan 171, 2020 Antwerpen, Belgium
* Author to whom correspondence should be addressed.
Received: 1 November 1999; Accepted: 19 January 2000 / Published: 18 February 2000
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Abstract: 4-O-Methylcedrusin, a minor component in ‘sangre de drago’, has been synthesized using a strategy of successive protection and deprotection reactions under very mild conditions. The key step of this synthesis is a selective protection of a catechol group as a cyclic carbonate in the presence of an isolated phenol group.
Keywords: Carbonates; lignans; phenolics; protecting groups; natural products

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MDPI and ACS Style

Van Dyck, S.M.O.; Lemière, G.L.F.; Jonckers, T.H.M.; Dommisse, R. Synthesis of 4-O-Methylcedrusin. Selective Protection of Catechols with Diphenyl Carbonate. Molecules 2000, 5, 153-161.

AMA Style

Van Dyck SMO, Lemière GLF, Jonckers THM, Dommisse R. Synthesis of 4-O-Methylcedrusin. Selective Protection of Catechols with Diphenyl Carbonate. Molecules. 2000; 5(2):153-161.

Chicago/Turabian Style

Van Dyck, Stefaan M.O.; Lemière, Guy L.F.; Jonckers, Tim H.M.; Dommisse, Roger. 2000. "Synthesis of 4-O-Methylcedrusin. Selective Protection of Catechols with Diphenyl Carbonate." Molecules 5, no. 2: 153-161.

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