Molecules 2000, 5(12), 1439-1460; doi:10.3390/51201439

Cyclohexenonic Long-Chain Fatty Alcohols as Neuronal Growth Stimulators

1 Laboratoire de Chimie Organique des Substances Naturelles, UMR CNRS 7509, Centre de Neurochimie, Université Louis Pasteur, 5, rue Blaise Pascal, 67084 Strasbourg cedex, France 2 Laboratoire de Neurophysiologie Cellulaire et Integrée, UMR CNRS 7519, Université Louis Pasteur, Strasbourg, France
* Author to whom correspondence should be addressed.
Received: 13 November 2000; in revised form: 7 December 2000 / Accepted: 7 December 2000 / Published: 22 December 2000
PDF Full-text Download PDF Full-Text [231 KB, uploaded 9 October 2008 15:37 CEST]
Abstract: Neurotrophic factors play an important role in the development and maintenance of neurons, thus providing a suitable therapeutic approach for the treatment of neurodegenerative diseases. However, their clinical use has revealed problematic because of a number of technical and biological disadvantages. Among the different strategies proposed to overcome such difficulties, the search for non-peptide substances with neurotrophic potential is giving promising results. Here we will expose major findings in this field, drawing special attention to cyclohexenonic long-chain fatty alcohols, a novel family of compounds that promote neuronal survival and neurite outgrowth.
Keywords: cyclohexenonic long-chain fatty alcohol; neurite outgrowth; neuronal survival; neurotrophic compound; neurotrophic factor; NGF; synthesis

Article Statistics

Load and display the download statistics.

Citations to this Article

Cite This Article

MDPI and ACS Style

Luu, B.; De Aguilar, J.-L.G.; Girlanda-Junges, C. Cyclohexenonic Long-Chain Fatty Alcohols as Neuronal Growth Stimulators. Molecules 2000, 5, 1439-1460.

AMA Style

Luu B, De Aguilar J-LG, Girlanda-Junges C. Cyclohexenonic Long-Chain Fatty Alcohols as Neuronal Growth Stimulators. Molecules. 2000; 5(12):1439-1460.

Chicago/Turabian Style

Luu, Bang; De Aguilar, José-Luis G.; Girlanda-Junges, Céline. 2000. "Cyclohexenonic Long-Chain Fatty Alcohols as Neuronal Growth Stimulators." Molecules 5, no. 12: 1439-1460.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert