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Molecules 1999, 4(7), 232-237; doi:10.3390/40700232
Article

Bifunctional Derivative of p,p'-Dichlorochalcone. Part II. Synthesis of a Novel Compound 2-[2-Carboxymethylthio-2-(4-chlorophenyl)ethyl]-2-(4-chlorophenyl)-4-thiazolidinone

1, 1, 1,* , 2
,
2 and 2
1 Department of Chemistry, Aligarh Muslim University, Aligarh-202002, India 2 Department of Chemistry (Natural Products), University of Antwerp (RUCA), Groenenborgerlaan 171, B-2020 Antwerp, Belgium
* Author to whom correspondence should be addressed.
Received: 3 March 1999 / Accepted: 10 June 1999 / Published: 19 July 1999
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Abstract

The synthesis of 2-[2-carboxymethylthio-2-(4-chlorophenyl) ethyl]-2-(4-chlorophenyl) - 4-thiazolidinone (1) from p, p'- dichlorochalcone using thioglycollic acid in the presence of ammonium carbonate is described. Structural assignment and stereochemistry are discussed.
Keywords: Organic synthesis; chalcone; thiazolidinone; 1H-NMR; 13C-NMR Organic synthesis; chalcone; thiazolidinone; 1H-NMR; 13C-NMR
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Mukhtar, S.; Rahman, M.V.; Ansari, W.H.; Lemière, G.; De Groot, A.; Dommisse, R. Bifunctional Derivative of p,p'-Dichlorochalcone. Part II. Synthesis of a Novel Compound 2-[2-Carboxymethylthio-2-(4-chlorophenyl)ethyl]-2-(4-chlorophenyl)-4-thiazolidinone. Molecules 1999, 4, 232-237.

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