A New Routine for the Synthesis of N-substituted-N-(sulfonyl) bromoacetamides with ZnCl2 as a Catalyst

doi:10.3390/40800238

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Molecules 1999, 4(8), 238-244; doi:10.3390/40800238

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A New Routine for the Synthesis of N-substituted-N-(sulfonyl) bromoacetamides with ZnCl₂ as a Catalyst

Martin Trávnícek and Milan Potácek*

Department of Organic Chemistry, Masaryk University, 611 37 Brno, Czech Republic

* Author to whom correspondence should be addressed.

Received: 28 June 1999 / Accepted: 7 July 1999 / Published: 13 August 1999

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Abstract: A series of N-acylated N-substituted sulfonamides was prepared for the first time in good yields and with excellent conversion by the reaction of N-substituted-N-(p-toluene) sulfonamides (1) with acetyl chloride and bromoacetyl bromide (2), respectively, in the presence of a catalytic amount of anhydrous ZnCl₂.

Keywords: Synthesis; ZnCl2 catalyst; N-substituted-N-(p-toluenesulfonyl) acetamides; Nbromacetyl-(+)- 2; 10-bornanesultam

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MDPI and ACS Style

Trávnícek, M.; Potácek, M. A New Routine for the Synthesis of N-substituted-N-(sulfonyl) bromoacetamides with ZnCl₂ as a Catalyst. Molecules 1999, 4, 238-244.

AMA Style

Trávnícek M, Potácek M. A New Routine for the Synthesis of N-substituted-N-(sulfonyl) bromoacetamides with ZnCl₂ as a Catalyst. Molecules. 1999; 4(8):238-244.

Chicago/Turabian Style

Trávnícek, Martin; Potácek, Milan. 1999. "A New Routine for the Synthesis of N-substituted-N-(sulfonyl) bromoacetamides with ZnCl₂ as a Catalyst." Molecules 4, no. 8: 238-244.

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