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Molecules 1999, 4(8), 238-244; doi:10.3390/40800238
Article

A New Routine for the Synthesis of N-substituted-N-(sulfonyl) bromoacetamides with ZnCl2 as a Catalyst

 and *
Department of Organic Chemistry, Masaryk University, 611 37 Brno, Czech Republic
* Author to whom correspondence should be addressed.
Received: 28 June 1999 / Accepted: 7 July 1999 / Published: 13 August 1999
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Abstract

A series of N-acylated N-substituted sulfonamides was prepared for the first time in good yields and with excellent conversion by the reaction of N-substituted-N-(p-toluene) sulfonamides (1) with acetyl chloride and bromoacetyl bromide (2), respectively, in the presence of a catalytic amount of anhydrous ZnCl2.
Keywords: Synthesis; ZnCl2 catalyst; N-substituted-N-(p-toluenesulfonyl) acetamides; Nbromacetyl-(+)- 2; 10-bornanesultam Synthesis; ZnCl2 catalyst; N-substituted-N-(p-toluenesulfonyl) acetamides; Nbromacetyl-(+)- 2; 10-bornanesultam
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Trávnícek, M.; Potácek, M. A New Routine for the Synthesis of N-substituted-N-(sulfonyl) bromoacetamides with ZnCl2 as a Catalyst. Molecules 1999, 4, 238-244.

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