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Molecules 1999, 4(8), 238-244; doi:10.3390/40800238
Article

A New Routine for the Synthesis of N-substituted-N-(sulfonyl) bromoacetamides with ZnCl2 as a Catalyst

 and
*
Department of Organic Chemistry, Masaryk University, 611 37 Brno, Czech Republic
* Author to whom correspondence should be addressed.
Received: 28 June 1999 / Accepted: 7 July 1999 / Published: 13 August 1999
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Abstract

A series of N-acylated N-substituted sulfonamides was prepared for the first time in good yields and with excellent conversion by the reaction of N-substituted-N-(p-toluene) sulfonamides (1) with acetyl chloride and bromoacetyl bromide (2), respectively, in the presence of a catalytic amount of anhydrous ZnCl2.
Keywords: Synthesis; ZnCl2 catalyst; N-substituted-N-(p-toluenesulfonyl) acetamides; Nbromacetyl-(+)- 2; 10-bornanesultam Synthesis; ZnCl2 catalyst; N-substituted-N-(p-toluenesulfonyl) acetamides; Nbromacetyl-(+)- 2; 10-bornanesultam
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Trávnícek, M.; Potácek, M. A New Routine for the Synthesis of N-substituted-N-(sulfonyl) bromoacetamides with ZnCl2 as a Catalyst. Molecules 1999, 4, 238-244.

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