Next Article in Journal
Synthesis of Novel Fused Heterocycles Based on Pyrano[2,3-c]pyrazole
Previous Article in Journal
Intramolecular Cycloaddition of Imines of Cysteine Derivatives
Article Menu

Article Versions

Export Article

Open AccessArticle
Molecules 1998, 3(3), 64-70; doi:10.3390/30300064

An Asymmetric Synthetic Approach to the A-ring of the Taxol Family of Anti-Cancer Compounds

Department of Chemistry, Imperial College of Science, Technology and Medicine, London SW7 2AY, UK
*
Author to whom correspondence should be addressed.
Received: 10 January 1998 / Accepted: 16 February 1998 / Published: 20 February 1998
Download PDF [52 KB, uploaded 18 June 2014]

Abstract

A synthetic route developed for the preparation of the A-ring of Taxol family of molecules is reported. By means of an intramolecular Diels-Alder reaction an asymmetric approach to this ring has been accomplished. Also, initial studies to prepare the A ring using an intramolecular Diels-Alder reaction have been successful.
Keywords: Taxol; cation-mediated cascade cyclisation; asymmetric Diels-Alder reaction Taxol; cation-mediated cascade cyclisation; asymmetric Diels-Alder reaction
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Craig, D.; Marin, M.L. An Asymmetric Synthetic Approach to the A-ring of the Taxol Family of Anti-Cancer Compounds. Molecules 1998, 3, 64-70.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top