Molecules 1998, 3(3), 64-70; doi:10.3390/30300064
Article

An Asymmetric Synthetic Approach to the A-ring of the Taxol Family of Anti-Cancer Compounds

Department of Chemistry, Imperial College of Science, Technology and Medicine, London SW7 2AY, UK
* Author to whom correspondence should be addressed.
Received: 10 January 1998; Accepted: 16 February 1998 / Published: 20 February 1998
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Abstract: A synthetic route developed for the preparation of the A-ring of Taxol family of molecules is reported. By means of an intramolecular Diels-Alder reaction an asymmetric approach to this ring has been accomplished. Also, initial studies to prepare the A ring using an intramolecular Diels-Alder reaction have been successful.
Keywords: Taxol; cation-mediated cascade cyclisation; asymmetric Diels-Alder reaction

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MDPI and ACS Style

Craig, D.; Marin, M.L. An Asymmetric Synthetic Approach to the A-ring of the Taxol Family of Anti-Cancer Compounds. Molecules 1998, 3, 64-70.

AMA Style

Craig D, Marin ML. An Asymmetric Synthetic Approach to the A-ring of the Taxol Family of Anti-Cancer Compounds. Molecules. 1998; 3(3):64-70.

Chicago/Turabian Style

Craig, D.; Marin, M. L. 1998. "An Asymmetric Synthetic Approach to the A-ring of the Taxol Family of Anti-Cancer Compounds." Molecules 3, no. 3: 64-70.

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