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A Short and Efficient Synthesis of (R)-Phoracantholide I
Bio-Organic Division, Bhabha Atomic Research Centre, Mumbai - 400 085, India
* Author to whom correspondence should be addressed.
Received: 16 January 1998; Accepted: 26 January 1998 / Published: 13 February 1998
Abstract: A short and efficient chemoenzymatic synthesis of the title compound has been developed. The salient features of the synthesis were i) preparation of the required chiron via a porcine pancreatic lipase (PPL) catalyzed esterification of a ω-functionalized 2-alkanol and ii) use of easily accessible and inexpensive materials/ reagents.
Keywords: Phoracantholide I; enantioselective synthesis; lipase catalyzed resolution
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MDPI and ACS Style
Sharma, A.; Chattopadhyay, S. A Short and Efficient Synthesis of (R)-Phoracantholide I. Molecules 1998, 3, 44-47.
Sharma A, Chattopadhyay S. A Short and Efficient Synthesis of (R)-Phoracantholide I. Molecules. 1998; 3(2):44-47.
Sharma, A.; Chattopadhyay, S. 1998. "A Short and Efficient Synthesis of (R)-Phoracantholide I." Molecules 3, no. 2: 44-47.