Antioxidation and Melanogenesis Inhibition of Various Dendrobium tosaense Extracts
AbstractThis study investigated the polyphenol content, antioxidant activity, and inhibition ability of mushroom tyrosinase and melanogenesis of Dendrobium tosaense (DT) extract. Ground DT was extracted using deionized water (W) or 50% ethanol (50E) at room temperature (RT) or 50 °C (50T) for 20 min. The 50T + 50E extract exhibited the highest total phenol content 47.0 ± 4.0 mg gallic acid equivalent/g DT extract, the highest level of 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) free-radical scavenging 66.0 ± 3.0 mg Trolox equivalent/g DT extract, and the highest reducing power 12.00 ± 0.50 mg vitamin C equivalent/g DT extract. The RT + W extract had the highest total flavonoid content 110.0 ± 3.0 mg quercetin equivalent/g DT extract. The RT + 50E extract had the lowest half maximal inhibitory concentration 1.30 ± 0.00 mg/mL for 2,2-diphenyl-1-picrylhydrazyl free-radical scavenging, and the lowest half maximal inhibitory concentration 6.40 ± 0.30 mg/mL for mushroom tyrosinase inhibition activity. DT extracts, especially RT + W and 50T + W, exhibited potent inhibitory effects on melanogenesis of B16/F10 cells. These results demonstrated the application potential of DT extract for skincare. View Full-Text
Share & Cite This Article
Chan, C.-F.; Wu, C.-T.; Huang, W.-Y.; Lin, W.-S.; Wu, H.-W.; Huang, T.-K.; Chang, M.-Y.; Lin, Y.-S. Antioxidation and Melanogenesis Inhibition of Various Dendrobium tosaense Extracts. Molecules 2018, 23, 1810.
Chan C-F, Wu C-T, Huang W-Y, Lin W-S, Wu H-W, Huang T-K, Chang M-Y, Lin Y-S. Antioxidation and Melanogenesis Inhibition of Various Dendrobium tosaense Extracts. Molecules. 2018; 23(7):1810.Chicago/Turabian Style
Chan, Chin-Feng; Wu, Chin-Tung; Huang, Wen-Ying; Lin, Wen-Shin; Wu, Han-Wei; Huang, Teng-Kuan; Chang, Min-Yun; Lin, Yung-Sheng. 2018. "Antioxidation and Melanogenesis Inhibition of Various Dendrobium tosaense Extracts." Molecules 23, no. 7: 1810.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.