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Molecules 2018, 23(7), 1570; https://doi.org/10.3390/molecules23071570

Drug Delivery Systems from Self-Assembly of Dendron-Polymer Conjugates

1
Department of Chemistry, Bogazici University, Bebek, 34342 Istanbul, Turkey
2
Center for Life Sciences and Technologies, Bogazici University, 34342 Istanbul, Turkey
Dedicated to Prof. Donald A. Tomalia on occasion of his 80th birthday.
*
Authors to whom correspondence should be addressed.
Academic Editor: Ashok Kakkar
Received: 18 May 2018 / Revised: 20 June 2018 / Accepted: 21 June 2018 / Published: 28 June 2018
Full-Text   |   PDF [6307 KB, uploaded 28 June 2018]   |  

Abstract

This review highlights the utilization of dendron-polymer conjugates as building blocks for the fabrication of nanosized drug delivery vehicles. The examples given provide an overview of the evolution of these delivery platforms, from simple micellar containers to smart stimuli- responsive drug delivery systems through their design at the macromolecular level. Variations in chemical composition and connectivity of the dendritic and polymeric segments provide a variety of self-assembled micellar nanostructures that embody desirable attributes of viable drug delivery systems. View Full-Text
Keywords: dendrimer; dendron; conjugates; nanotherapeutics; drug delivery; polymers dendrimer; dendron; conjugates; nanotherapeutics; drug delivery; polymers
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
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Bolu, B.S.; Sanyal, R.; Sanyal, A. Drug Delivery Systems from Self-Assembly of Dendron-Polymer Conjugates . Molecules 2018, 23, 1570.

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