Encapsulation of Gold Nanostructures and Oil-in-Water Nanocarriers in Microgels with Biomedical Potential
Abstract
:1. Introduction
2. Results and Discussion
2.1. Synthesis and Characterization of Gold Nanostructures
2.2. Development and Characterization of Curcumin-Loaded O/W Nanoemulsions (CurNem), and Viability Assays
2.3. Development and Characterization of Alginate Microgels Loaded with Gold Nanostructures and CurNem
3. Materials and Methods
3.1. Materials
3.2. Synthesis and Characterization of Gold Nanostructures
3.2.1. Synthesis and Characterization of Gold Nanospheres (GNS)
3.2.2. Synthesis and Characterization of Gold Nanorods (GNR)
3.2.3. Irradiation of Gold Nanostructures
3.3. Elaboration of Curcumin-Loaded O/W Nanoemulsions (CurNem)
3.4. In Vitro Determination of Efficacy and Safety of CurNem
3.4.1. Stability of CurNem in Cell Culture Medium
3.4.2. Cell Culture
3.4.3. Viability Assays
3.5. Development and Characterization of Alginate Microgels Loaded with Gold Nanostructures and CurNem
Irradiation of Microgels Containing CurNem and Gold Nanostructures
3.6. Statistical Analysis
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Conflicts of Interest
References
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Sample Availability: Samples of the compounds are not available from the authors. |
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Inostroza-Riquelme, M.; Vivanco, A.; Lara, P.; Guerrero, S.; Salas-Huenuleo, E.; Chamorro, A.; Leyton, L.; Bolaños, K.; Araya, E.; Quest, A.F.G.; et al. Encapsulation of Gold Nanostructures and Oil-in-Water Nanocarriers in Microgels with Biomedical Potential. Molecules 2018, 23, 1208. https://doi.org/10.3390/molecules23051208
Inostroza-Riquelme M, Vivanco A, Lara P, Guerrero S, Salas-Huenuleo E, Chamorro A, Leyton L, Bolaños K, Araya E, Quest AFG, et al. Encapsulation of Gold Nanostructures and Oil-in-Water Nanocarriers in Microgels with Biomedical Potential. Molecules. 2018; 23(5):1208. https://doi.org/10.3390/molecules23051208
Chicago/Turabian StyleInostroza-Riquelme, Mariela, Andrea Vivanco, Pablo Lara, Simón Guerrero, Edison Salas-Huenuleo, Alejandro Chamorro, Lisette Leyton, Karen Bolaños, Eyleen Araya, Andrew F. G. Quest, and et al. 2018. "Encapsulation of Gold Nanostructures and Oil-in-Water Nanocarriers in Microgels with Biomedical Potential" Molecules 23, no. 5: 1208. https://doi.org/10.3390/molecules23051208