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Molecules 2018, 23(5), 1170; https://doi.org/10.3390/molecules23051170

A Review: The Bioactivities and Pharmacological Applications of Polygonatum sibiricum polysaccharides

1
School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China
2
School of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China
*
Author to whom correspondence should be addressed.
Received: 14 April 2018 / Revised: 7 May 2018 / Accepted: 8 May 2018 / Published: 14 May 2018
(This article belongs to the Section Natural Products Chemistry)
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Abstract

Traditional Chinese Medicine (TCM) has been widely used in China and is regarded as the most important therapeutic. Polygonatum sibiricum (PS), a natural plant used in traditional Chinese medicine, has various functions associated with a number of its components. There are many compositions in PS including polysaccharides, steroids, anthraquinone, alkaloids, cardiac glycosides, lignin, vitamins, various acids, and so on. Of these, polysaccharides play a significant role in PS-based therapeutics. This article summarizes Polygonatum sibiricum polysaccharides (PSP) have many pharmacological applications and biological activities, such as their antioxidant activity, anti-aging activity, an anti-fatigue effect, immunity enhancement effect, antibacterial effect, anti-inflammatory effect, hypolipidemic and antiatherosclerotic effects, anti-osteoporosis effect, liver protection, treatment of diabetes mellitus (DM), anti-cancer effect, and may help prevent Alzheimer’s disease, and so on. This review summarized the extraction method, purification method, compositions, pharmacological applications, biological activities, biosynthesis, and prospects of PSP, providing a basis for further study of PS and PSP. View Full-Text
Keywords: Polygonatum sibiricum polysaccharides (PSP); compositions; pharmacological applications; biological activity; biosythesis; prospects Polygonatum sibiricum polysaccharides (PSP); compositions; pharmacological applications; biological activity; biosythesis; prospects
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Cui, X.; Wang, S.; Cao, H.; Guo, H.; Li, Y.; Xu, F.; Zheng, M.; Xi, X.; Han, C. A Review: The Bioactivities and Pharmacological Applications of Polygonatum sibiricum polysaccharides. Molecules 2018, 23, 1170.

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