Next Article in Journal
Lewis Pair Polymerization for New Reactivity and Structure in Polymer Synthesis
Next Article in Special Issue
Probing the Inhibitor versus Chaperone Properties of sp2-Iminosugars towards Human β-Glucocerebrosidase: A Picomolar Chaperone for Gaucher Disease
Previous Article in Journal
Poly(vinyl Chloride) Photostabilization in the Presence of Schiff Bases Containing a Thiadiazole Moiety
Previous Article in Special Issue
Potent GH20 N-Acetyl-β-d-hexosaminidase Inhibitors: N-Substituted 3-acetamido-4-amino-5-hydroxymethyl-cyclopentanediols
Article Menu
Issue 4 (April) cover image

Export Article

Open AccessFeature PaperCommunication
Molecules 2018, 23(4), 914; doi:10.3390/molecules23040914

One-Pot, Highly Stereoselective Synthesis of Dithioacetal-α,α-Diglycosides

Laboratoire d’Innovation Moléculaire et Application (LIMA), Université de Strasbourg, Université de Haute-Alsace, CNRS (UMR 7042), Equipe Synthèse Organique et Molécules Bioactives (SYBIO), Ecole Européenne de Chimie, Polymères et Matériaux, 25 rue Becquerel, 67000 Strasbourg, France
These authors contributed equally to the work.
*
Author to whom correspondence should be addressed.
Received: 28 March 2018 / Revised: 12 April 2018 / Accepted: 13 April 2018 / Published: 15 April 2018
(This article belongs to the Special Issue Glycomimetics: Design, Synthesis and Therapeutic Applications)
View Full-Text   |   Download PDF [1157 KB, uploaded 16 April 2018]   |  

Abstract

A one-step access to dithioacetal-α,α-diglycosides is reported. The synthetic strategy is based on the thioacetalization of aldehydes or ketones via highly stereoselective ring-opening of 1,6 anhydrosugars with bis(trimethylsilyl)sulfide. View Full-Text
Keywords: glycomimetics; thioglycosides; dithioacetals; 1,6-anhydrosugars; ring-opening glycomimetics; thioglycosides; dithioacetals; 1,6-anhydrosugars; ring-opening
Figures

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

Share & Cite This Article

MDPI and ACS Style

Céspedes Dávila, M.F.; Schneider, J.P.; Godard, A.; Hazelard, D.; Compain, P. One-Pot, Highly Stereoselective Synthesis of Dithioacetal-α,α-Diglycosides. Molecules 2018, 23, 914.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top