Prenylated Polyphenols from Broussonetia kazinoki as Inhibitors of Nitric Oxide Production
Abstract
:1. Introduction
2. Results and Discussion
3. Materials and Methods
3.1. Plant Material, Extraction, Isolation, and Sample Preparation
3.2. Cell Culture
3.3. Measurement of Nitric Oxide Production and Cell Viability
3.4. Western Blot Analysis
3.5. Reverse Transcription and Polymerase Chain Reaction (RT-PCR) Analysis
3.6. Measurement of NF-κB Activity
3.7. Statistical Analysis
4. Conclusions
Supplementary Materials
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Sample Availability: Samples of the compounds are not available from the authors. |
Compounds | IC50 (µM) 1 |
---|---|
1 | >20 |
2 | 5.2 ± 0.2 |
3 | 4.2 ± 0.2 |
4 | 5.3 ± 0.4 |
5 | 16.9 ± 1.1 |
6 | 5.0 ± 0.4 |
7 | 8.0 ± 0.5 |
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Lee, D.Y.; Lee, H.J.; Ryu, J.-H. Prenylated Polyphenols from Broussonetia kazinoki as Inhibitors of Nitric Oxide Production. Molecules 2018, 23, 639. https://doi.org/10.3390/molecules23030639
Lee DY, Lee HJ, Ryu J-H. Prenylated Polyphenols from Broussonetia kazinoki as Inhibitors of Nitric Oxide Production. Molecules. 2018; 23(3):639. https://doi.org/10.3390/molecules23030639
Chicago/Turabian StyleLee, Da Yeon, Hwa Jin Lee, and Jae-Ha Ryu. 2018. "Prenylated Polyphenols from Broussonetia kazinoki as Inhibitors of Nitric Oxide Production" Molecules 23, no. 3: 639. https://doi.org/10.3390/molecules23030639