Cytotoxic Compounds from Aloe megalacantha
AbstractPhytochemical investigation of the ethyl acetate extract of the roots of Aloe megalacantha led to the isolation of four new natural products—1,8-dimethoxynepodinol (1), aloesaponarin III (2), 10-O-methylchrysalodin (3) and methyl-26-O-feruloyl-oxyhexacosanate (4)—along with ten known compounds. All purified metabolites were characterized by NMR, mass spectrometric analyses and comparison with literature data. The isolates were evaluated for their cytotoxic activity against a human cervix carcinoma cell line KB-3-1 and some of them exhibited good activity, with aloesaponarin II (IC50 = 0.98 µM) being the most active compound. View Full-Text
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Abdissa, N.; Gohlke, S.; Frese, M.; Sewald, N. Cytotoxic Compounds from Aloe megalacantha. Molecules 2017, 22, 1136.
Abdissa N, Gohlke S, Frese M, Sewald N. Cytotoxic Compounds from Aloe megalacantha. Molecules. 2017; 22(7):1136.Chicago/Turabian Style
Abdissa, Negera; Gohlke, Sebastian; Frese, Marcel; Sewald, Norbert. 2017. "Cytotoxic Compounds from Aloe megalacantha." Molecules 22, no. 7: 1136.
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