Structural Characterization and Antifungal Studies of Zinc-Doped Hydroxyapatite Coatings
AbstractThe present study is focused on the synthesis, characterization and antifungal evaluation of zinc-doped hydroxyapatite (Zn:HAp) coatings. The Zn:HAp coatings were deposited on a pure Si (Zn:HAp_Si) and Ti (Zn:HAp_Ti) substrate by a sol-gel dip coating method using a zinc-doped hydroxyapatite nanogel. The nature of the crystal phase was determined by X-ray diffraction (XRD). The crystalline phase of the prepared Zn:HAp composite was assigned to hexagonal hydroxyapatite in the P63/m space group. The colloidal properties of the resulting Zn:HAp (xZn = 0.1) nanogel were analyzed by Dynamic Light Scattering (DLS) and zeta potential. Scanning Electron Microscopy (SEM) was used to investigate the morphology of the zinc-doped hydroxyapatite (Zn:HAp) nanogel composite and Zn:HAp coatings. The elements Ca, P, O and Zn were found in the Zn:HAp composite. According to the EDX results, the degree of Zn substitution in the structure of Zn:HAp composite was 1.67 wt%. Moreover, the antifungal activity of Zn:HAp_Si and Zn:HAp_Ti against Candida albicans (C. albicans) was evaluated. A decrease in the number of surviving cells was not observed under dark conditions, whereas under daylight and UV light illumination a major decrease in the number of surviving cells was observed. View Full-Text
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Iconaru, S.L.; Prodan, A.M.; Buton, N.; Predoi, D. Structural Characterization and Antifungal Studies of Zinc-Doped Hydroxyapatite Coatings. Molecules 2017, 22, 604.
Iconaru SL, Prodan AM, Buton N, Predoi D. Structural Characterization and Antifungal Studies of Zinc-Doped Hydroxyapatite Coatings. Molecules. 2017; 22(4):604.Chicago/Turabian Style
Iconaru, Simona L.; Prodan, Alina M.; Buton, Nicolas; Predoi, Daniela. 2017. "Structural Characterization and Antifungal Studies of Zinc-Doped Hydroxyapatite Coatings." Molecules 22, no. 4: 604.
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