Quinoline-Based Hybrid Compounds with Antimalarial Activity
AbstractThe application of quinoline-based compounds for the treatment of malaria infections is hampered by drug resistance. Drug resistance has led to the combination of quinolines with other classes of antimalarials resulting in enhanced therapeutic outcomes. However, the combination of antimalarials is limited by drug-drug interactions. In order to overcome the aforementioned factors, several researchers have reported hybrid compounds prepared by reacting quinoline-based compounds with other compounds via selected functionalities. This review will focus on the currently reported quinoline-based hybrid compounds and their preclinical studies. View Full-Text
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Nqoro, X.; Tobeka, N.; Aderibigbe, B.A. Quinoline-Based Hybrid Compounds with Antimalarial Activity. Molecules 2017, 22, 2268.
Nqoro X, Tobeka N, Aderibigbe BA. Quinoline-Based Hybrid Compounds with Antimalarial Activity. Molecules. 2017; 22(12):2268.Chicago/Turabian Style
Nqoro, Xhamla; Tobeka, Naki; Aderibigbe, Blessing A. 2017. "Quinoline-Based Hybrid Compounds with Antimalarial Activity." Molecules 22, no. 12: 2268.
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