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Molecules 2017, 22(12), 2073; doi:10.3390/molecules22122073

Metabolites Produced by an Endophytic Phomopsis sp. and Their Anti-TMV Activity

1
Key Laboratory of Bio-Pesticide and Chemistry-Biology, Ministry of Education, Fujian Agriculture and Forestry University, Fuzhou 350002, China
2
Key Laboratory of Plant Virology of Fujian Province, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou 350002, China
*
Authors to whom correspondence should be addressed.
Received: 19 September 2017 / Revised: 8 November 2017 / Accepted: 25 November 2017 / Published: 27 November 2017
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Abstract

The fermentation and isolation of metabolites produced by an endophytic fungus, which was identified as Phomopsis sp. FJBR-11, based on phylogenetic analysis, led to the identification of six compounds, including dothiorelones A–C, and H, and cytosporones C and U. Among these compounds, cytosporone U exhibited potent inhibitory activity against Tobacco mosaic virus (TMV). Moreover, the crude and a purified exopolysaccharide were proved to possess strong inhibitory effects against the virus infection. View Full-Text
Keywords: Phomopsis; dothiorelone; cytosporone; Tobacco mosaic virus Phomopsis; dothiorelone; cytosporone; Tobacco mosaic virus
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MDPI and ACS Style

Tan, Q.-W.; Fang, P.-H.; Ni, J.-C.; Gao, F.; Chen, Q.-J. Metabolites Produced by an Endophytic Phomopsis sp. and Their Anti-TMV Activity. Molecules 2017, 22, 2073.

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