A Search for Dual Action HIV-1 Reverse Transcriptase, Bacterial RNA Polymerase Inhibitors
AbstractUsing molecular modeling approach, potential antibacterial agents with triazole core were proposed. A moderate to weak level of antibacterial activity in most of the compounds have been observed, with best minimal inhibitory concentration (MIC) value of 0.003 mg/mL, as shown by the 15 against S. epidermidis. Studied compounds were also submitted to the antifungal assay. The best antifungal activity was detected for 16 with MIC at 0.125 and 0.25 mg/mL against C. albicans and C. parapsilosis, respectively. View Full-Text
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Paneth, A.; Frączek, T.; Grzegorczyk, A.; Janowska, D.; Malm, A.; Paneth, P. A Search for Dual Action HIV-1 Reverse Transcriptase, Bacterial RNA Polymerase Inhibitors. Molecules 2017, 22, 1808.
Paneth A, Frączek T, Grzegorczyk A, Janowska D, Malm A, Paneth P. A Search for Dual Action HIV-1 Reverse Transcriptase, Bacterial RNA Polymerase Inhibitors. Molecules. 2017; 22(11):1808.Chicago/Turabian Style
Paneth, Agata; Frączek, Tomasz; Grzegorczyk, Agnieszka; Janowska, Dominika; Malm, Anna; Paneth, Piotr. 2017. "A Search for Dual Action HIV-1 Reverse Transcriptase, Bacterial RNA Polymerase Inhibitors." Molecules 22, no. 11: 1808.
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