Microbial Glycosylation of Daidzein, Genistein and Biochanin A: Two New Glucosides of Biochanin A
AbstractBiotransformation of daidzein, genistein and biochanin A by three selected filamentous fungi was investigated. As a result of biotransformations, six glycosylation products were obtained. Fungus Beauveria bassiana converted all tested isoflavones to 4″-O-methyl-7-O-glucosyl derivatives, whereas Absidia coerulea and Absidia glauca were able to transform genistein and biochanin A to genistin and sissotrin, respectively. In the culture of Absidia coerulea, in addition to the sissotrin, the product of glucosylation at position 5 was formed. Two of the obtained compounds have not been published so far: 4″-O-methyl-7-O-glucosyl biochanin A and 5-O-glucosyl biochanin A (isosissotrin). Biotransformation products were obtained with 22%–40% isolated yield. View Full-Text
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Sordon, S.; Popłoński, J.; Tronina, T.; Huszcza, E. Microbial Glycosylation of Daidzein, Genistein and Biochanin A: Two New Glucosides of Biochanin A. Molecules 2017, 22, 81.
Sordon S, Popłoński J, Tronina T, Huszcza E. Microbial Glycosylation of Daidzein, Genistein and Biochanin A: Two New Glucosides of Biochanin A. Molecules. 2017; 22(1):81.Chicago/Turabian Style
Sordon, Sandra; Popłoński, Jarosław; Tronina, Tomasz; Huszcza, Ewa. 2017. "Microbial Glycosylation of Daidzein, Genistein and Biochanin A: Two New Glucosides of Biochanin A." Molecules 22, no. 1: 81.
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