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Molecules 2017, 22(1), 143; doi:10.3390/molecules22010143

Identification of Phenolic Compounds from Hancornia speciosa (Apocynaceae) Leaves by UHPLC Orbitrap-HRMS

1
Departamento de Ciências Farmacêuticas, Universidade Federal da Paraíba, João Pessoa 58051-900, Brazil
2
Dept. Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, Halle 06120, Germany
3
Departamento de Farmácia, Universidade Federal do Rio Grande do Norte, Natal 59010-180, Brazil
These authors contributed equally to this paper.
*
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 23 November 2016 / Revised: 12 January 2017 / Accepted: 13 January 2017 / Published: 15 January 2017
(This article belongs to the Section Natural Products)
View Full-Text   |   Download PDF [708 KB, uploaded 19 January 2017]   |  

Abstract

Apocynaceae is a botanical family distributed mainly in tropical and subtropical regions of the world. In Brazil, they comprise about 90 genera and 850 species, inhabiting various types of vegetation. Within this large botanical family, the genus Hancornia is considered monotypic, with its only species Hancornia speciosa Gomes. Antihypertensive, antidiabetic, and antiviral activities are described for this species. Despite having been the target of some studies, knowledge of its chemical composition is still limited. In this study, the phenolics of H. speciosa leaves were analyzed using ultra-high performance liquid chromatography (UHPLC) coupled to Orbitrap high-resolution mass spectrometry (HRMS). As a result, 14 compounds were identified viz. protocatechuic acid, catechin, and quercetin, and another 14 were putatively identified viz. B- and C-type procyanidins, while just one compound remained unknown. From the identified compounds, 17 are reported for the first time viz. coumaroylquinic acid isomers and eriodyctiol. The results show that Hancornia speciosa can serve as source of valuable phenolics. View Full-Text
Keywords: Hancornia speciosa; mangabeira; UHPLC; Orbitrap; chemical composition; phenolic compounds Hancornia speciosa; mangabeira; UHPLC; Orbitrap; chemical composition; phenolic compounds
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Bastos, K.X.; Dias, C.N.; Nascimento, Y.M.; da Silva, M.S.; Langassner, S.M.Z.; Wessjohann, L.A.; Tavares, J.F. Identification of Phenolic Compounds from Hancornia speciosa (Apocynaceae) Leaves by UHPLC Orbitrap-HRMS. Molecules 2017, 22, 143.

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