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Molecules 2017, 22(1), 133; doi:10.3390/molecules22010133

New Phenylpropanoid and Coumarin Glycosides from the Stems of Hydrangea paniculata Sieb

State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
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Academic Editor: Derek J. McPhee
Received: 16 December 2016 / Revised: 6 January 2017 / Accepted: 9 January 2017 / Published: 18 January 2017
(This article belongs to the Section Natural Products)
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Abstract

A new phenylpropanoid glycoside (1), and two new coumarin glycosides (2, 3), together with two known compounds (4, 5), have been isolated from the stems of Hydrangea paniculata Sieb. Their structures have been determined by spectroscopic and chemical methods. Furthermore, compound 1 (50 μM) exhibited significant hepatoprotective activity against N-acetyl-p-aminophenol (APAP)-induced HepG2 cell damage in vitro assays. View Full-Text
Keywords: Hydrangea paniculata; phenylpropanoid glycoside; coumarin glycoside; hepatoprotective activity Hydrangea paniculata; phenylpropanoid glycoside; coumarin glycoside; hepatoprotective activity
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MDPI and ACS Style

Ma, J.; Li, C.-J.; Yang, J.-Z.; Sun, H.; Zhang, D.-M. New Phenylpropanoid and Coumarin Glycosides from the Stems of Hydrangea paniculata Sieb. Molecules 2017, 22, 133.

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