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Molecules 2016, 21(7), 947; doi:10.3390/molecules21070947

Identification of Chemical Composition of Leaves and Flowers from Paeonia rockii by UHPLC-Q-Exactive Orbitrap HRMS

1
College of Pharmacy, Southwest University for Nationalities, Chengdu 610041, China
2
Department of Biological and Chemical Engineering, Chongqing University of Education, Chongqing 400067, China
3
Chongqing Institute for Food and Drug Control, Chongqing 401120, China
*
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 8 May 2016 / Revised: 14 July 2016 / Accepted: 15 July 2016 / Published: 21 July 2016
(This article belongs to the Section Natural Products)
View Full-Text   |   Download PDF [1278 KB, uploaded 21 July 2016]   |  

Abstract

The Paeonia genus, an important source of crude drugs, has been extensively used in traditional Chinese medicine (TCM) to treat cardiovascular and female-related diseases. Although many peony species have been investigated, the study of Paeonia rockii is still quite limited, especially its chemical composition. Here, an advanced ultra-high-performance liquid chromatography (UHPLC) analytical technique combined with Q-Exactive Orbitrap hybrid quadrupole-Orbitrap mass spectrometry utilizing high-resolution full MS and MS/MS scan modes was applied to screen and identify the chemical constituents of this species. As a result, a total of 46 compounds were characterized, including 11 monoterpene glycosides, five phenolic acids, six tannins and 24 flavonoids. Among them, 16 compounds were reported for the first time in Paeonia rockii. View Full-Text
Keywords: Paeonia rockii; UHPLC-Q-Exactive Orbitrap HRMS; chemical composition; high-resolution mass spectrometry Paeonia rockii; UHPLC-Q-Exactive Orbitrap HRMS; chemical composition; high-resolution mass spectrometry
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Li, J.; Kuang, G.; Chen, X.; Zeng, R. Identification of Chemical Composition of Leaves and Flowers from Paeonia rockii by UHPLC-Q-Exactive Orbitrap HRMS. Molecules 2016, 21, 947.

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