Uprolides N, O and P from the Panamanian Octocoral Eunicea succinea
AbstractThree new diterpenes, uprolide N (1), uprolide O (2), uprolide P (3) and a known one, dolabellane (4), were isolated from the CH2Cl2-MeOH extract of the gorgonian octocoral Eunicea succinea, collected from Bocas del Toro, on the Caribbean coast of Panama. Their structures were determined using spectroscopic analyses, including 1D and 2D NMR and high-resolution mass spectrometry (HRMS) together with molecular modeling studies. Compounds 1–3 displayed anti-inflammatory properties by inhibiting production of Tumor Necrosis Factor (TNF) and Interleukin (IL)-6 induced by lipopolysaccharide (LPS) in murine macrophages. View Full-Text
- Supplementary File 1:
Supplementary (PDF, 11895 KB)
Share & Cite This Article
Torres-Mendoza, D.; González, Y.; Gómez-Reyes, J.F.; Guzmán, H.M.; López-Perez, J.L.; Gerwick, W.H.; Fernandez, P.L.; Gutiérrez, M. Uprolides N, O and P from the Panamanian Octocoral Eunicea succinea. Molecules 2016, 21, 819.
Torres-Mendoza D, González Y, Gómez-Reyes JF, Guzmán HM, López-Perez JL, Gerwick WH, Fernandez PL, Gutiérrez M. Uprolides N, O and P from the Panamanian Octocoral Eunicea succinea. Molecules. 2016; 21(6):819.Chicago/Turabian Style
Torres-Mendoza, Daniel; González, Yisett; Gómez-Reyes, José F.; Guzmán, Héctor M.; López-Perez, José L.; Gerwick, William H.; Fernandez, Patricia L.; Gutiérrez, Marcelino. 2016. "Uprolides N, O and P from the Panamanian Octocoral Eunicea succinea." Molecules 21, no. 6: 819.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.