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Molecules 2016, 21(11), 1605; doi:10.3390/molecules21111605

Chemical Constituents of Phaius mishmensis

1
Department of Chemistry, National Cheng Kung University, Tainan 701, Taiwan
2
School of Pharmacy, China Medical University, Taichung 40402, Taiwan
3
Department of Anatomy, School of Medicine, China Medical University, Taichung 40402, Taiwan
4
Research Center for Chinese Herbal Medicine, China Medical University, Taichung 40402, Taiwan
*
Authors to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 5 October 2016 / Revised: 18 November 2016 / Accepted: 21 November 2016 / Published: 23 November 2016
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Abstract

The partitioned n-hexane, CHCl3, and EtOAc extracts from the crude MeOH extract of Phaius mishmensis showed considerable cytotoxicities against the human breast carcinoma (MCF-7), lung carcinoma (NCI-H460), and central nervous system carcinoma (SF-268) cell lines. Four new compounds, phaindole (1), (7′R,8′R)-phaithrene (2), methyl 3-hydroxy-4,5-dimethoxypropiophenone (3), and methyl hematinate (4), as well as 44 known compounds were isolated from the MeOH extract of Phaius mishmensis. The structures of the compounds were determined using spectroscopic methods. View Full-Text
Keywords: Phaius mishmensis; Orchidaceae; phaindole; (7′R,8′R)-phaithrene; methyl 3-hydroxy-4,5-dimethoxypropiophenone; methyl hematinate Phaius mishmensis; Orchidaceae; phaindole; (7′R,8′R)-phaithrene; methyl 3-hydroxy-4,5-dimethoxypropiophenone; methyl hematinate
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Jao, C.-W.; Hung, T.-H.; Chang, C.-F.; Chuang, T.-H. Chemical Constituents of Phaius mishmensis. Molecules 2016, 21, 1605.

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