The Scavenging of DPPH, Galvinoxyl and ABTS Radicals by Imine Analogs of Resveratrol
AbstractResveratrol (3,5,4′-trihydroxystilbene) is a phytoalexin produced by plants. Resveratrol is known for its anti-cancer, antiviral and antioxidant properties. We prepared imine analogs of resveratrol ((hydroxyphenyliminomethyl)phenols) and tested their antioxidant activity. All prepared resveratrol analogs were able to scavenge 2,2-diphenyl-1-picrylhydrazyl (DPPH), galvinoxyl radical (GOR) and 2,2′-azino-bis(3-ethylbenzothiazoline)-6-sulphonic acid (ABTS) radicals. The antioxidant activity efficiency correlated with the number and position of hydroxyl groups. The most effective antioxidants were resveratrol analogs containing three hydroxyl groups in the benzylidene part of their molecules. These results provide new insights into the relationship between the chemical structure and biological activity of resveratrol analogs. View Full-Text
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Kotora, P.; Šeršeň, F.; Filo, J.; Loos, D.; Gregáň, J.; Gregáň, F. The Scavenging of DPPH, Galvinoxyl and ABTS Radicals by Imine Analogs of Resveratrol. Molecules 2016, 21, 127.
Kotora P, Šeršeň F, Filo J, Loos D, Gregáň J, Gregáň F. The Scavenging of DPPH, Galvinoxyl and ABTS Radicals by Imine Analogs of Resveratrol. Molecules. 2016; 21(1):127.Chicago/Turabian Style
Kotora, Peter; Šeršeň, František; Filo, Juraj; Loos, Dušan; Gregáň, Juraj; Gregáň, Fridrich. 2016. "The Scavenging of DPPH, Galvinoxyl and ABTS Radicals by Imine Analogs of Resveratrol." Molecules 21, no. 1: 127.
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