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Molecules 2015, 20(8), 14936-14949; doi:10.3390/molecules200814936

Eco-Friendly Synthesis of a New Class of Pyridinium-Based Ionic Liquids with Attractive Antimicrobial Activity

Department of Chemistry, Taibah University, Al-Madina Al-Mounawara 30002, Saudi Arabia
Academic Editor: Jason P. Hallett
Received: 16 June 2015 / Revised: 30 July 2015 / Accepted: 5 August 2015 / Published: 14 August 2015
(This article belongs to the Special Issue Ionic Liquids in Organic Synthesis)
View Full-Text   |   Download PDF [713 KB, uploaded 14 August 2015]   |  

Abstract

The present study reports a green synthesis of a new family of ionic liquids (ILs) based on functionalized 4-dimethylaminopyridinium derivatives. The structures of 23 newly synthesized ILs (224) were confirmed by FT-IR, 1H-, 13C-, 11B-, 19F-, and 31P-NMR spectroscopy and mass spectrometry. The antimicrobial activity of all novel ILs was tested against a panel of bacteria and fungi. The results prove that all tested ILs are effective antibacterial and antifungal agents, especially 4-(dimethylamino)-1-(4-phenoxybutyl) pyridinium derivatives 5 and 19. View Full-Text
Keywords: eco-friendly synthesis; ultrasound irradiation; ionic liquid; antimicrobial activity eco-friendly synthesis; ultrasound irradiation; ionic liquid; antimicrobial activity
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Messali, M. Eco-Friendly Synthesis of a New Class of Pyridinium-Based Ionic Liquids with Attractive Antimicrobial Activity. Molecules 2015, 20, 14936-14949.

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