Stable Hemiaminals: 2-Aminopyrimidine Derivatives
AbstractStable hemiaminals can be obtained in the one-pot reaction between 2-aminopyrimidine and nitrobenzaldehyde derivatives. Ten new hemiaminals have been obtained, six of them in crystal state. The molecular stability of these intermediates results from the presence of both electron-withdrawing nitro groups as substituents on the phenyl ring and pyrimidine ring, so no further stabilisation by intramolecular interaction is required. Hemiaminal molecules possess a tetrahedral carbon atom constituting a stereogenic centre. As the result of crystallisation in centrosymmetric space groups both enantiomers are present in the crystal structure. View Full-Text
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Kwiecień, A.; Ciunik, Z. Stable Hemiaminals: 2-Aminopyrimidine Derivatives. Molecules 2015, 20, 14365-14376.
Kwiecień A, Ciunik Z. Stable Hemiaminals: 2-Aminopyrimidine Derivatives. Molecules. 2015; 20(8):14365-14376.Chicago/Turabian Style
Kwiecień, Anna; Ciunik, Zbigniew. 2015. "Stable Hemiaminals: 2-Aminopyrimidine Derivatives." Molecules 20, no. 8: 14365-14376.