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Molecules 2015, 20(7), 12817-12840; doi:10.3390/molecules200712817

Recent Advances in the Synthesis of Carotenoid-Derived Flavours and Fragrances

Istituto di Chimica del Riconoscimento Molecolare, Via Mancinelli 7, I-20131 Milano, Italy
Academic Editor: Luca Forti
Received: 14 May 2015 / Revised: 2 July 2015 / Accepted: 8 July 2015 / Published: 15 July 2015
(This article belongs to the Collection Recent Advances in Flavors and Fragrances)

Abstract

Carotenoids are important isoprenoid compounds whose oxidative degradation produces a plethora of smaller derivatives, called apocarotenoids, which possess a range of different chemical structures and biological activities. Among these natural products, compounds having less than 15 carbon atoms in their frameworks are often relevant flavours or fragrances and their manufacturing represents an important economic resource for chemical companies. The strict correlation between stereochemical structure and odour has made the stereospecific synthesis of the latter biological active compounds increasingly important. In this review, the recent advances on the synthesis of the most relevant carotenoid-derived flavours and fragrances are discussed. In particular, the new synthetic methods that have given new and innovative perspectives from a scientific standpoint and the preparative approaches that might possess industrial importance are described thoroughly. View Full-Text
Keywords: carotenoids; apocarotenoids; flavours; fragrances; organic synthesis; stereoselective synthesis; resolution; enzymes carotenoids; apocarotenoids; flavours; fragrances; organic synthesis; stereoselective synthesis; resolution; enzymes
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Serra, S. Recent Advances in the Synthesis of Carotenoid-Derived Flavours and Fragrances. Molecules 2015, 20, 12817-12840.

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