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Molecules 2015, 20(7), 12670-12685; doi:10.3390/molecules200712670

Synthesis, Structure and Antioxidant Activity of Cyclohexene-Fused Selenuranes and Related Derivatives

1
Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai 400076, India
2
Department of Chemistry, Howard University, Washington, DC 20059, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Thomas G. Back
Received: 30 April 2015 / Revised: 30 June 2015 / Accepted: 6 July 2015 / Published: 13 July 2015
(This article belongs to the Special Issue Selenium Catalysts and Antioxidants)
View Full-Text   |   Download PDF [1689 KB, uploaded 13 July 2015]   |  

Abstract

Synthesis, structure and antioxidant activity of new cyclohexene-fused spiroselenuranes and a spirotellurane is reported. Oxidation reactions of bis(o-formylcyclohex- 1-ene)selenide/bis(2-hydroxymethylcyclohex-1-ene)selenide provide the corresponding spiroselenuranes. The glutathione peroxidase-like activity of the newly synthesized compounds has been evaluated. View Full-Text
Keywords: spirodioxychalcogenuranes; glutathione peroxidase (GPx); antioxidant; monochalcogenides; Se–O linkage spirodioxychalcogenuranes; glutathione peroxidase (GPx); antioxidant; monochalcogenides; Se–O linkage
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Prasad, P.R.; Singh, H.B.; Butcher, R.J. Synthesis, Structure and Antioxidant Activity of Cyclohexene-Fused Selenuranes and Related Derivatives. Molecules 2015, 20, 12670-12685.

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