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Molecules 2015, 20(6), 9640-9655; doi:10.3390/molecules20069640

Multidisciplinary Approach to Determine the Optimal Time and Period for Extracting the Essential Oil from Mentha suaveolens Ehrh

1
Department of Drug Chemistry and Technology, "Sapienza" University, P.le Aldo Moro 5, 00185 Rome, Italy
2
Rome Center for Molecular Design, Department of Drug Chemistry and Technology, "Sapienza" University, P.le Aldo Moro 5, 00185 Rome, Italy
3
Department of Public Health and Infectious Diseases, "Sapienza" University, P.le Aldo Moro 5, 00185 Rome, Italy
4
Department of Physiology and Pharmacology "Vittorio Erspamer", "Sapienza" University, P.le Aldo Moro 5, 00185 Rome, Italy
Rino Ragno dedicates this work to his friend Aldo Peparello, passed away prematurely, without him this study would not have be thought.
*
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 13 March 2015 / Revised: 15 May 2015 / Accepted: 18 May 2015 / Published: 26 May 2015
(This article belongs to the Section Natural Products)
View Full-Text   |   Download PDF [733 KB, uploaded 26 May 2015]   |  

Abstract

A comprehensive study on essential oils (EOs) extracted from some Mentha suaveolens L. samples, collected in the countryside of Tarquinia, is reported. In this study, the procedure for essential oil preparation, in terms of harvesting and extraction time, was analyzed in detail for the first time. The GC/MS analysis, carried out on 18 samples, revealed that piperitenone oxide (PO), the main essential oils’ chemical constituent, is primarily responsible for the related antifungal activity. Nevertheless, EOs with lower PO content indicate that other chemicals, such as para-cymenene, may participate in exerting the EOs’ antifungal effect. Furthermore, the bacterial reverse mutation assay highlighted lack of mutagenic effect in all tested samples. Analysis of the results indicated that for higher activity, the essential oils should be produced with 3 h maximum hydrodistillation, regardless of the harvesting time. Differently, the maximum essential oil yield can be obtained in August and the highest piperitenone oxide percentage is obtainable in July. View Full-Text
Keywords: Mentha suaveolens; GC/MS, essential oils; piperitenone oxide Mentha suaveolens; GC/MS, essential oils; piperitenone oxide
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Garzoli, S.; Pirolli, A.; Vavala, E.; Di Sotto, A.; Sartorelli, G.; Božović, M.; Angiolella, L.; Mazzanti, G.; Pepi, F.; Ragno, R. Multidisciplinary Approach to Determine the Optimal Time and Period for Extracting the Essential Oil from Mentha suaveolens Ehrh . Molecules 2015, 20, 9640-9655.

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