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Molecules 2015, 20(2), 2492-2509; doi:10.3390/molecules20022492

Production and Characterization of Cosmetic Nanoemulsions Containing Opuntia ficus-indica (L.) Mill Extract as Moisturizing Agent

1
College of Pharmacy, Federal University of Rio Grande do Norte, Rua Gustavo Cordeiro de Farias, s/n, Petrópolis, Natal 59012-570, RN, Brazil
2
College of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Avenida Zeferino Vaz, s/n, Monte Alegre, Ribeirão Preto 14040-903, SP, Brazil
*
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 20 November 2014 / Revised: 11 December 2014 / Accepted: 6 January 2015 / Published: 2 February 2015
(This article belongs to the Section Natural Products)
View Full-Text   |   Download PDF [752 KB, uploaded 10 February 2015]   |  

Abstract

This study aimed to produce and characterize an oil in water (O/W) nanoemulsion containing Opuntia ficus-indica (L.) Mill hydroglycolic extract, as well as evaluate its preliminary and accelerated thermal stability and moisturizing efficacy. The formulations containing 0.5% of xanthan gum (FX) and 0.5% of xanthan gum and 1% of Opuntia ficus-indica Mill extract (FXE) were white, homogeneous and fluid in aspect. Both formulations were stable during preliminary and accelerated stability tests. FX and FXE presented a pH compatible to skin pH (4.5–6.0); droplet size varying from 92.2 to 233.6 nm; a polydispersion index (PDI) around 0.200 and a zeta potential from −26.71 to −47.01 mV. FXE was able to increase the water content of the stratum corneum for 5 h after application on the forearm. The O/W nanoemulsions containing 1% of Opuntia ficus-indica (L.) Mill extract presented suitable stability for at least for 60 days. Besides, this formulation was able to increase the water content of stratum corneum, showing its moisturizing efficacy. View Full-Text
Keywords: nanoemulsions; Opuntia ficus-indica; non-invasive methods; emulsions; formulation/stability; skin barrier nanoemulsions; Opuntia ficus-indica; non-invasive methods; emulsions; formulation/stability; skin barrier
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Ribeiro, R.C.A.; Barreto, S.M.A.G.; Ostrosky, E.A.; Rocha-Filho, P.A.; Veríssimo, L.M.; Ferrari, M. Production and Characterization of Cosmetic Nanoemulsions Containing Opuntia ficus-indica (L.) Mill Extract as Moisturizing Agent. Molecules 2015, 20, 2492-2509.

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