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Molecules 2014, 19(5), 5599-5610; doi:10.3390/molecules19055599
Article

Non-Conventional Methodologies in the Synthesis of 1-Indanones

1
,
2
,
1
,
1
,
3
,
4
 and
1,*
1 Dipartimento di Scienze della Salute, Università Magna Graecia, Viale Europa, Germaneto (CZ) 88100, Italy 2 Dipartimento di Chimica, Università della Calabria, Cubo 12C, Arcavacata di Rende (CS) 87036, Italy 3 Dipartimento di Scienza e Tecnologia del Farmaco, Università di Torino, Via Pietro Giuria 9, Torino 10125, Italy 4 Dipartimento Scienza del Farmaco e Prodotti per la salute, Università di Messina, Via Santissima Annunziata, Messina 98168, Italy,
* Author to whom correspondence should be addressed.
Received: 2 April 2014 / Revised: 19 April 2014 / Accepted: 23 April 2014 / Published: 30 April 2014
(This article belongs to the Section Organic Synthesis)
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Abstract

1-Indanones have been successfully prepared by means of three different non-conventional techniques, namely microwaves, high-intensity ultrasound and a Q-tube™ reactor. A library of differently substituted 1-indanones has been prepared via one-pot intramolecular Friedel-Crafts acylation and their efficiency and “greenness” have been compared.
Keywords: 1-indanones; microwaves; ultrasound; Q-tube™; Friedel-Crafts acylation 1-indanones; microwaves; ultrasound; Q-tube™; Friedel-Crafts acylation
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Oliverio, M.; Nardi, M.; Costanzo, P.; Cariati, L.; Cravotto, G.; Giofrè, S.V.; Procopio, A. Non-Conventional Methodologies in the Synthesis of 1-Indanones. Molecules 2014, 19, 5599-5610.

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