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Molecules 2014, 19(5), 5611-5623; doi:10.3390/molecules19055611
Article

miRNAs for the Detection of MultiDrug Resistance: Overview and Perspectives

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Received: 18 February 2014; in revised form: 23 April 2014 / Accepted: 25 April 2014 / Published: 30 April 2014
(This article belongs to the Special Issue miRNAs as Probes to Monitor Cancer and Neurodegenerative Disorders)
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Abstract: The goal of the present paper is to establish and validate the link between cancer diagnosis and therapy by microRNAs detection. The induction in vitro of some specific microRNAs after treatment with MDR ligands has been outlined. Starting from the results obtained by in vitro induction of MDCK and MDCK-MDR1 cells treated by a MDR1 ligand, a new scenario in the early diagnosis and chemotherapy could be disclosed. To corroborate this perspective a short overview on pancreatic cancer diagnosis and chemotherapeutic treatment has been reported.
Keywords: microRNAs; MDR; early diagnosis; MDCK-MDR1; P-glycoprotein microRNAs; MDR; early diagnosis; MDCK-MDR1; P-glycoprotein
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Gisel, A.; Valvano, M.; El Idrissi, I.G.; Nardulli, P.; Azzariti, A.; Carrieri, A.; Contino, M.; Colabufo, N.A. miRNAs for the Detection of MultiDrug Resistance: Overview and Perspectives. Molecules 2014, 19, 5611-5623.

AMA Style

Gisel A, Valvano M, El Idrissi IG, Nardulli P, Azzariti A, Carrieri A, Contino M, Colabufo NA. miRNAs for the Detection of MultiDrug Resistance: Overview and Perspectives. Molecules. 2014; 19(5):5611-5623.

Chicago/Turabian Style

Gisel, Andreas; Valvano, Mirna; El Idrissi, Imane G.; Nardulli, Patrizia; Azzariti, Amalia; Carrieri, Antonio; Contino, Marialessandra; Colabufo, Nicola A. 2014. "miRNAs for the Detection of MultiDrug Resistance: Overview and Perspectives." Molecules 19, no. 5: 5611-5623.


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