Next Article in Journal
Effects of Piperine on the Intestinal Permeability and Pharmacokinetics of Linarin in Rats
Next Article in Special Issue
The Role of microRNA in Head and Neck Cancer: Current Knowledge and Perspectives
Previous Article in Journal
Non-Conventional Methodologies in the Synthesis of 1-Indanones
Previous Article in Special Issue
Role of MicroRNA in Response to Ionizing Radiations: Evidences and Potential Impact on Clinical Practice for Radiotherapy
Molecules 2014, 19(5), 5611-5623; doi:10.3390/molecules19055611
Article

miRNAs for the Detection of MultiDrug Resistance: Overview and Perspectives

1
, 1
, 2
, 3
, 3
, 4
, 4
 and 2,4,*
Received: 18 February 2014; in revised form: 23 April 2014 / Accepted: 25 April 2014 / Published: 30 April 2014
(This article belongs to the Special Issue miRNAs as Probes to Monitor Cancer and Neurodegenerative Disorders)
View Full-Text   |   Download PDF [200 KB, uploaded 18 June 2014]
Abstract: The goal of the present paper is to establish and validate the link between cancer diagnosis and therapy by microRNAs detection. The induction in vitro of some specific microRNAs after treatment with MDR ligands has been outlined. Starting from the results obtained by in vitro induction of MDCK and MDCK-MDR1 cells treated by a MDR1 ligand, a new scenario in the early diagnosis and chemotherapy could be disclosed. To corroborate this perspective a short overview on pancreatic cancer diagnosis and chemotherapeutic treatment has been reported.
Keywords: microRNAs; MDR; early diagnosis; MDCK-MDR1; P-glycoprotein microRNAs; MDR; early diagnosis; MDCK-MDR1; P-glycoprotein
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Gisel, A.; Valvano, M.; El Idrissi, I.G.; Nardulli, P.; Azzariti, A.; Carrieri, A.; Contino, M.; Colabufo, N.A. miRNAs for the Detection of MultiDrug Resistance: Overview and Perspectives. Molecules 2014, 19, 5611-5623.

AMA Style

Gisel A, Valvano M, El Idrissi IG, Nardulli P, Azzariti A, Carrieri A, Contino M, Colabufo NA. miRNAs for the Detection of MultiDrug Resistance: Overview and Perspectives. Molecules. 2014; 19(5):5611-5623.

Chicago/Turabian Style

Gisel, Andreas; Valvano, Mirna; El Idrissi, Imane G.; Nardulli, Patrizia; Azzariti, Amalia; Carrieri, Antonio; Contino, Marialessandra; Colabufo, Nicola A. 2014. "miRNAs for the Detection of MultiDrug Resistance: Overview and Perspectives." Molecules 19, no. 5: 5611-5623.


Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert