Three New Ring-A Modified Ursane Triterpenes from Davidia involucrata
Abstract
:1. Introduction
2. Results and Discussion
Compounds | Cell lines | ||
---|---|---|---|
SGC-7901 | MCF-7 | BEL-7404 | |
1 | – a | – | – |
2 | Nt | Nt | Nt |
3 | 36.3 ± 2.00 | 37.4 ± 1.57 | 47.41 ± 20.4 |
4 | – | – | – |
5 | – | – | – |
6 | 42.35 ± 1.79 | 45.8 ± 2.15 | 38.24 ± 1.57 |
7 | 39.25 ± 1.83 | 21.24 ± 1.15 | 24.59 ± 1.51 |
8 | 7.26 ± 0.08 | 12.37 ± 0.18 | 8.15 ± 0.13 |
9 | 10.26 ± 0.52 | 15.21 ± 0.28 | 18.14 ± 0.30 |
Doxorubicin | 0.19 ± 0.032 | 0.08 ± 0.007 | 0.12 ± 0.011 |
3. Experimental Section
3.1. General
3.2. Plant Material
3.3. Extraction and Isolation
No. | 1 a | 2 b | 3 b | |||
---|---|---|---|---|---|---|
δC (DEPT) | δH, mult. (J in Hz) | δC (DEPT) | δH, mult. (J in Hz) | δC (DEPT) | δH, mult. (J in Hz) | |
1 | 50.3 (CH2) | 0.97 d (11.5), 2.09 dd (11.5, 7.5) | 56.5 (CH2) | 2.07 s | 43.9 (CH2) | 1.30 m, 2.03 m |
3.4. Spectral Data
3.5. Cytotoxicity Assay
4. Conclusions
Supplementary Materials
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Tan, Q.-W.; Ouyang, M.-A.; Gao, B. Three New Ring-A Modified Ursane Triterpenes from Davidia involucrata. Molecules 2014, 19, 4897-4906. https://doi.org/10.3390/molecules19044897
Tan Q-W, Ouyang M-A, Gao B. Three New Ring-A Modified Ursane Triterpenes from Davidia involucrata. Molecules. 2014; 19(4):4897-4906. https://doi.org/10.3390/molecules19044897
Chicago/Turabian StyleTan, Qing-Wei, Ming-An Ouyang, and Bo Gao. 2014. "Three New Ring-A Modified Ursane Triterpenes from Davidia involucrata" Molecules 19, no. 4: 4897-4906. https://doi.org/10.3390/molecules19044897