Next Article in Journal
Substrate Specificity and Enzyme Recycling Using Chitosan Immobilized Laccase
Previous Article in Journal
A New Urease Inhibitor from Viola betonicifolia
Article Menu
Issue 10 (October) cover image

Export Article

Open AccessArticle
Molecules 2014, 19(10), 16779-16793; doi:10.3390/molecules191016779

Biomimetic Adhesive Materials Containing Cyanoacryl Group for Medical Application

1
Orthopaedic Department, College of Medicine, Chosun University, Gwangju 501-759, Korea
2
College of General Education, Chosun University, Gwangju 501-759, Korea
*
Author to whom correspondence should be addressed.
Received: 17 August 2014 / Revised: 19 September 2014 / Accepted: 25 September 2014 / Published: 17 October 2014
(This article belongs to the Section Organic Synthesis)
View Full-Text   |   Download PDF [1642 KB, uploaded 17 October 2014]   |  

Abstract

For underwater adhesives with biocompatible and more flexible bonds using biomimetic adhesive groups, DOPA-like adhesive molecules were modified with cyanoacrylates to obtain different repeating units and chain length copolymers. The goal of this work is to copy the mechanisms of underwater bonding to create synthetic water-borne underwater medical adhesives through blending of the modified DOPA and a triblock copolymer (PEO-PPO-PEO) for practical application to repair wet living tissues and bones, and in turn, to use the synthetic adhesives to test mechanistic hypotheses about the natural adhesive. The highest values in stress and modulus of the biomimetic adhesives prepared in wet state were 165 kPa and 33 MPa, respectively. View Full-Text
Keywords: biomimetic adhesive; PEO-PPO-PEO triblock copolymer; coacervate; DOPA; under water adhesive; cyanoacrylate biomimetic adhesive; PEO-PPO-PEO triblock copolymer; coacervate; DOPA; under water adhesive; cyanoacrylate
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Jo, S.H.; Sohn, J.S. Biomimetic Adhesive Materials Containing Cyanoacryl Group for Medical Application. Molecules 2014, 19, 16779-16793.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top