Molecules 2013, 18(9), 10776-10788; doi:10.3390/molecules180910776
Article

A Highly Efficient Regioselective Addition of Acetylides to Enediones Based on Steric Effects

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Received: 19 July 2013; in revised form: 20 August 2013 / Accepted: 20 August 2013 / Published: 3 September 2013
(This article belongs to the Section Organic Synthesis)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: A simple and efficient strategy for the synthesis of 1-ethynylcyclohex-2-enol derivatives was developed utilizing regioselective addition of acetylides to enediones based on steric effects. Further investigation of the substrate scope of enediones indicated that all the addition reactions ocurred in good yield.
Keywords: regioselective addition; acetylides; enediones; steric effects; 1-ethynylcyclohex-2-enol derivatives
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MDPI and ACS Style

Han, X.; Wan, C.; Yang, D.; Yuan, X.; Du, S.; Xiao, Y.; Qin, Z. A Highly Efficient Regioselective Addition of Acetylides to Enediones Based on Steric Effects. Molecules 2013, 18, 10776-10788.

AMA Style

Han X, Wan C, Yang D, Yuan X, Du S, Xiao Y, Qin Z. A Highly Efficient Regioselective Addition of Acetylides to Enediones Based on Steric Effects. Molecules. 2013; 18(9):10776-10788.

Chicago/Turabian Style

Han, Xiaoqiang; Wan, Chuan; Yang, Dongyan; Yuan, Xiaoyong; Du, Shijie; Xiao, Yumei; Qin, Zhaohai. 2013. "A Highly Efficient Regioselective Addition of Acetylides to Enediones Based on Steric Effects." Molecules 18, no. 9: 10776-10788.

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