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Molecules 2013, 18(9), 10465-10483; doi:10.3390/molecules180910465

Biological Activities and Phytochemicals of Swietenia macrophylla King

Biomolecular Research Group, Biochemistry Program, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia
* Author to whom correspondence should be addressed.
Received: 24 June 2013 / Revised: 16 August 2013 / Accepted: 24 August 2013 / Published: 30 August 2013
(This article belongs to the Section Metabolites)
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Swietenia macrophylla King (Meliaceae) is an endangered and medicinally important plant indigenous to tropical and subtropical regions of the World. S. macrophylla has been widely used in folk medicine to treat various diseases. The review reveals that limonoids and its derivatives are the major constituents of S. macrophylla. There are several data in the literature indicating a great variety of pharmacological activities of S. macrophylla, which exhibits antimicrobial, anti-inflammatory, antioxidant effects, antimutagenic, anticancer, antitumor and antidiabetic activities. Various other activities like anti-nociceptive, hypolipidemic, antidiarrhoeal, anti-infective, antiviral, antimalarial, acaricidal, antifeedant and heavy metal phytoremediation activity have also been reported. In view of the immense medicinal importance of S. macrophylla, this review aimed at compiling all currently available information on its ethnomedicinal uses, phytochemistry and biological activities of S. macrophylla, showing its importance.
Keywords: Swietenia macrophylla; mahogany; limonoids; biological activity; phytochemicals Swietenia macrophylla; mahogany; limonoids; biological activity; phytochemicals
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Moghadamtousi, S.Z.; Goh, B.H.; Chan, C.K.; Shabab, T.; Kadir, H.A. Biological Activities and Phytochemicals of Swietenia macrophylla King. Molecules 2013, 18, 10465-10483.

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