Next Article in Journal
Anti-Inflammatory Effects of Total Isoflavones from Pueraria lobata on Cerebral Ischemia in Rats
Previous Article in Journal
Antitumor, Antioxidant and Antimicrobial Studies of Substituted Pyridylguanidines
Article Menu

Export Article

Open AccessArticle
Molecules 2013, 18(9), 10397-10403; doi:10.3390/molecules180910397

Three New Phenolics and Other Constituents from the Seeds of Lithocarpus pachylepis

Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100193, China
Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China
National Engineering Laboratory of Southwest Endangered Medicinal Resources Development, National Development and Reform Commission, Guangxi Botanical Garden of Medicinal Plant, Nanning 530023, China
These authors contributed equally to this work.
Author to whom correspondence should be addressed.
Received: 1 July 2013 / Revised: 25 August 2013 / Accepted: 26 August 2013 / Published: 28 August 2013
(This article belongs to the Section Natural Products)
View Full-Text   |   Download PDF [234 KB, uploaded 18 June 2014]   |  


Twelve phenolics, including the three new compounds balanophonin C (1), balanophonin D (2), balanophonin E (3), were isolated from the seeds of Lithocarpus pachylepis. Their structures were elucidated by various spectroscopic techniques (UV, IR, MS, 1D and 2D NMR). Compounds 19 were evaluated for their anti-inflammatory activities on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 and showed moderate inhibitory activities, with IC50 values ranging from 10.9 to 34.7 μM.
Keywords: Fagaceae; Lithocarpus pachylepis A Camus; phenolics; anti-inflammatory activities Fagaceae; Lithocarpus pachylepis A Camus; phenolics; anti-inflammatory activities
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Xie, Y.; Ma, G.; Wei, H.; Yuan, J.; Wu, H.; Zhou, X.; Yang, J.; Xu, X. Three New Phenolics and Other Constituents from the Seeds of Lithocarpus pachylepis. Molecules 2013, 18, 10397-10403.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top