Molecules 2013, 18(9), 10397-10403; doi:10.3390/molecules180910397
Article

Three New Phenolics and Other Constituents from the Seeds of Lithocarpus pachylepis

1 Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100193, China 2 Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China 3 National Engineering Laboratory of Southwest Endangered Medicinal Resources Development, National Development and Reform Commission, Guangxi Botanical Garden of Medicinal Plant, Nanning 530023, China These authors contributed equally to this work.
* Author to whom correspondence should be addressed.
Received: 1 July 2013; in revised form: 25 August 2013 / Accepted: 26 August 2013 / Published: 28 August 2013
(This article belongs to the Section Natural Products)
PDF Full-text Download PDF Full-Text [234 KB, uploaded 28 August 2013 11:02 CEST]
Abstract: Twelve phenolics, including the three new compounds balanophonin C (1), balanophonin D (2), balanophonin E (3), were isolated from the seeds of Lithocarpus pachylepis. Their structures were elucidated by various spectroscopic techniques (UV, IR, MS, 1D and 2D NMR). Compounds 19 were evaluated for their anti-inflammatory activities on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 and showed moderate inhibitory activities, with IC50 values ranging from 10.9 to 34.7 μM.
Keywords: Fagaceae; Lithocarpus pachylepis A Camus; phenolics; anti-inflammatory activities

Article Statistics

Load and display the download statistics.

Citations to this Article

Cite This Article

MDPI and ACS Style

Xie, Y.; Ma, G.; Wei, H.; Yuan, J.; Wu, H.; Zhou, X.; Yang, J.; Xu, X. Three New Phenolics and Other Constituents from the Seeds of Lithocarpus pachylepis. Molecules 2013, 18, 10397-10403.

AMA Style

Xie Y, Ma G, Wei H, Yuan J, Wu H, Zhou X, Yang J, Xu X. Three New Phenolics and Other Constituents from the Seeds of Lithocarpus pachylepis. Molecules. 2013; 18(9):10397-10403.

Chicago/Turabian Style

Xie, Yong; Ma, Guoxu; Wei, Hua; Yuan, Jingquan; Wu, Haifeng; Zhou, Xiaolei; Yang, Junshan; Xu, Xudong. 2013. "Three New Phenolics and Other Constituents from the Seeds of Lithocarpus pachylepis." Molecules 18, no. 9: 10397-10403.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert