Molecules 2013, 18(9), 10352-10366; doi:10.3390/molecules180910352
Article

Bioactive Protopanaxatriol Type Saponins Isolated from the Roots of Panax Notoginseng (Burk.) F. H. Chen

Received: 22 July 2013; in revised form: 12 August 2013 / Accepted: 20 August 2013 / Published: 26 August 2013
(This article belongs to the Section Natural Products)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Seven new protopanaxatriol type saponins, 20S-sanchirhinosides A1 (1), A2 (2), A3 (3), A4 (4), A5 (5), and A6 (6), and sanchirhinoside B (7) were obtained as minor constituents from the root extract of Panax notoginseng (Burkill, F. H. Chen), which showed protection effects against antimycin A induced mitochondrial oxidative stress. Their structures were elucidated by chemical and spectroscopic methods (IR, HRESI-TOF-MS, 1D and 2D NMR). Among them, compounds 4, 6 and 7 showed significant protective effects against antimycin A-induced L6 cell injury.
Keywords: Panax notoginseng; root; protopanaxatriol type saponins; L6 cell; mitochondrial oxidative stress
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MDPI and ACS Style

Zhang, Y.; Han, L.-F.; Sakah, K.J.; Wu, Z.-Z.; Liu, L.-L.; Agyemang, K.; Gao, X.-M.; Wang, T. Bioactive Protopanaxatriol Type Saponins Isolated from the Roots of Panax Notoginseng (Burk.) F. H. Chen. Molecules 2013, 18, 10352-10366.

AMA Style

Zhang Y, Han L-F, Sakah KJ, Wu Z-Z, Liu L-L, Agyemang K, Gao X-M, Wang T. Bioactive Protopanaxatriol Type Saponins Isolated from the Roots of Panax Notoginseng (Burk.) F. H. Chen. Molecules. 2013; 18(9):10352-10366.

Chicago/Turabian Style

Zhang, Yi; Han, Li-Feng; Sakah, Kaunda J.; Wu, Zhi-Zhen; Liu, Li-Li; Agyemang, Kojo; Gao, Xiu-Mei; Wang, Tao. 2013. "Bioactive Protopanaxatriol Type Saponins Isolated from the Roots of Panax Notoginseng (Burk.) F. H. Chen." Molecules 18, no. 9: 10352-10366.

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