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Molecules 2013, 18(7), 8298-8318; doi:10.3390/molecules18078298

The Genus Gnaphalium L. (Compositae): Phytochemical and Pharmacological Characteristics

2,* , 1,* , 2,3
1 College of Pharmacy, Yanbian University, Yanji 133002, Jilin, China 2 Institute of Phytochemistry, Jilin Academy of Chinese Medicine Sciences, Changchun 130012, Jilin, China 3 College of Resources and Environment, Jilin Agricultural University, Changchun 130118, Jilin, China
* Authors to whom correspondence should be addressed.
Received: 18 June 2013 / Revised: 8 July 2013 / Accepted: 12 July 2013 / Published: 15 July 2013
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The genus Gnaphalium, a herb distributed worldwide, comprises approximately 200 species of the Compositae (Asteraceae) family that belongs to the tribe Gnaphalieae. Some species are traditionally used as wild vegetables and in folk medicine. This review focuses on the phytochemical investigations and biological studies of plants from the genus Gnaphalium over the past few decades. More than 125 chemical constituents have been isolated from the genus Gnaphalium, including flavonoids, sesquiterpenes, diterpenes, triterpenes, phytosterols, anthraquinones, caffeoylquinic acid derivatives, and other compounds. The extracts of this genus, as well as compounds isolated from it, have been demonstrated to possess multiple pharmacological activities such as antioxidant, antibacterial and antifungal, anti-complement, antitussive and expectorant, insect antifeedant, cytotoxic, anti-inflammatory, antidiabetic and antihypouricemic properties. The present review compiles the information available on this genus because of its relevance to food and ethnopharmacology and the potential therapeutic uses of these species.
Keywords: Gnaphalium; chemical constituents; biological activities Gnaphalium; chemical constituents; biological activities
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Zheng, X.; Wang, W.; Piao, H.; Xu, W.; Shi, H.; Zhao, C. The Genus Gnaphalium L. (Compositae): Phytochemical and Pharmacological Characteristics. Molecules 2013, 18, 8298-8318.

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