Molecules 2013, 18(7), 7364-7375; doi:10.3390/molecules18077364
Communication

TDAE Strategy for the Synthesis of 2,3-Diaryl N-Tosylaziridines

, ,  and * email
Received: 27 May 2013; in revised form: 14 June 2013 / Accepted: 18 June 2013 / Published: 24 June 2013
(This article belongs to the Section Organic Synthesis)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: We report herein an original and rapid synthesis of 2,3-diaryl N-tosylaziridines by TDAE strategy starting from ortho- or para-nitro(dichloromethyl)benzene derivatives and N-tosylimines. A mixture of cis/trans isomers was isolated from 1-(dichloromethyl)-4-nitrobenzene, whereas only trans-aziridines were obtained from ortho-nitro derivatives.
Keywords: TDAE; N-tosylimines; aziridines; diastereoselectivity
PDF Full-text Download PDF Full-Text [285 KB, uploaded 18 June 2014 20:07 CEST]

Export to BibTeX |
EndNote


MDPI and ACS Style

Khoumeri, O.; Spitz, C.; Terme, T.; Vanelle, P. TDAE Strategy for the Synthesis of 2,3-Diaryl N-Tosylaziridines. Molecules 2013, 18, 7364-7375.

AMA Style

Khoumeri O, Spitz C, Terme T, Vanelle P. TDAE Strategy for the Synthesis of 2,3-Diaryl N-Tosylaziridines. Molecules. 2013; 18(7):7364-7375.

Chicago/Turabian Style

Khoumeri, Omar; Spitz, Cédric; Terme, Thierry; Vanelle, Patrice. 2013. "TDAE Strategy for the Synthesis of 2,3-Diaryl N-Tosylaziridines." Molecules 18, no. 7: 7364-7375.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert