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Chemical Constituents of the Root of Jasminum giraldii
Department of Pharmacology, School of Pharmacy, the Fourth Military Medical University, Xi'an 710032, Shaanxi, China
Collaborative Innovation Center for Chinese Medicine in Qingba Mountains, the Fourth Military Medical University, Xi'an 710032, Shaanxi, China
Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, Jiangsu, China
Xi'an Modern Chemistry Research Institute, Xi'an 710032, Shaanxi, China
These authors contributed equally to this work.
* Authors to whom correspondence should be addressed.
Received: 1 February 2013; in revised form: 26 March 2013 / Accepted: 12 April 2013 / Published: 22 April 2013
Abstract: Two new compounds, ethylconiferin (1) and (−)-lariciresinol 4-(6'''-O-cinnamyl-β-d-glucopyranoside) (2), along with the three known compounds (+)-pinoresinol (3), (+)-cycloolivil (4), nobiletin (5), were isolated from the root of Jasminum girialdii. All these compounds were isolated for the first time from this source. Their structures were elucidated on the basis of extensive spectroscopic analysis and chemical methods. In addition, the in vitro cytotoxic activity of these compounds was evaluated. The results showed that none of the compounds had any significant inhibitory activities on the proliferation of HCT-116 and SW-620 cells.
Keywords: Jasminum giraldii; oleaceae; chemical constituents; cytotoxic activity
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Yue, Z.; Qin, H.; Li, Y.; Sun, Y.; Wang, Z.; Yang, T.; Liu, L.; Wang, M.; Feng, F.; Mei, Q. Chemical Constituents of the Root of Jasminum giraldii. Molecules 2013, 18, 4766-4775.
Yue Z, Qin H, Li Y, Sun Y, Wang Z, Yang T, Liu L, Wang M, Feng F, Mei Q. Chemical Constituents of the Root of Jasminum giraldii. Molecules. 2013; 18(4):4766-4775.
Yue, Zhenggang; Qin, Hui; Li, Yuhua; Sun, Yang; Wang, Zhipeng; Yang, Tiehong; Liu, Li; Wang, Minchang; Feng, Feng; Mei, Qibing. 2013. "Chemical Constituents of the Root of Jasminum giraldii." Molecules 18, no. 4: 4766-4775.