Macrocyclic Spermidine Alkaloids from Androya decaryi L. Perrier
Abstract
:1. Introduction
2. Results and Discussion
δH (J in Hz) a | δC | |
---|---|---|
2 | 4.01 dd (11.5, 2.9) | 60.0 |
3 | 2.48 dd (15.0, 2.9); 2.56 dd (15.0, 11.5) | 45.0 |
4 | - | 171.7 |
5 | 8.57 bs | - |
6 | 3.19 dt (13.7, 5.5); 3.70 dt (13.7, 5.2) | 39.6 |
7 | 1.80–1.85 m | 27.8 |
8 | 2.86 dt (12.1, 5.0) 2.96 dt (12.1, 5.6) | 49.7 |
10 | 2.74–2.75 m | 49.1 |
11 | 1.55–1.61 m; 1.74–1.80 m | 27.9 |
12 | 1.40–1.49 m; 1.63–1.69 m | 27.6 |
13 | 2.33 ddd (12.5, 8.8, 1.9); 2.52–2.56 m | 45.8 |
1’ | - | 142.7 |
2'/6' | 7.23–7.27 m | 126.4 |
3'/5' | 7.30–7.36 m | 128.7 |
4' | 7.23–7.27 m | 127.3 |
2a | 2b | |||
---|---|---|---|---|
δH (J in Hz) a | δC | δH | δCa | |
2 | 3.56–3.62 m | 56.5 | 3.71–3.73, m | 57.05 |
3 | 2.22 dd (13.7, 2.3); 2.52–2.62 m | 41.9 | 2.40 dd (14.4, 3.8); 2.56–2.61 m | 40.4 |
4 | - | 173.2 | - | 173.9 |
5 | 7.45–7.53 m | - | 8.10 br s | - |
6 | 2.97–3.03 m; 4.12–4.21 m | 37.4 | 3.05–3.11 m; 3.76–3.81 m | 38.8 |
7 | 2.02–2.06 m; 2.42–2.52 m | 26.9 | 1.98–2.03 m; 2.20–2.26 m | 25.8 |
8 | 2.87–2.95 m; 3.27–3.36 m | 46.3 | 3.05–3.11 m; 3.16–3.22 m | 49.5 |
10 | 2.87–2.95 m; 3.21–3.27 m | 45.8 | 2.88 ddd (13.2, 11.5, 2.4); 2.97–3.01 m | 50.1 |
11 | 1.70–1.77 m; 1.94–2.02 m | 22.5 | 1.67–1.77 m; 1.98–2.09 m | 26.4 |
12 | 1.73–1.82 m | 22.1 | 1.57–1.78 m | 24.7 |
13 | 2.28–2.37 m; 2.87–2.93 m | 54.4 | 2.46–2.53 m; 2.56–2.61 m | 46.8 |
14 | 5.59 d (10.4) | 126.6 | 5.55–5.58 m | 126.95 |
15 | 5.79–5.84 m | 123.7 | 5.83 ddd (10.0, 4.3, 3.7) | 127.0 |
16 | 1.85–1.92 m; 2.28–2.37 m | 20.5 | 1.83–1.85 m | 22.2 |
17 | 2.73–2.79 m | 63.5 | 3.16–3.22 m | 57.0 |
18 | 3.53 dt (11.0, 1.8) | 73.0 | 3.54, ddd (9.5, 6.4, 5.2) | 72.2 |
19 | 1.61–1.77 m | 28.9 | 1.50–1.56 m | 26.7 |
20 | 1.13 t (7.4) | 10.7 | 1.06 t (7.3) | 10.4 |
3. Experimental
3.1. General
3.2. Plant Material
3.3. Extraction and Isolation
3.4. Antiplasmodial Bioassay
4. Conclusions
Supplementary Materials
Acknowledgments
References
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Le Lamer, A.-C.; Ibrahim, N.; Manjary, F.; Mallet-Ladeira, S.; Girardi, C.; Valentin, A.; Fabre, N.; Moulis, C. Macrocyclic Spermidine Alkaloids from Androya decaryi L. Perrier. Molecules 2013, 18, 3962-3971. https://doi.org/10.3390/molecules18043962
Le Lamer A-C, Ibrahim N, Manjary F, Mallet-Ladeira S, Girardi C, Valentin A, Fabre N, Moulis C. Macrocyclic Spermidine Alkaloids from Androya decaryi L. Perrier. Molecules. 2013; 18(4):3962-3971. https://doi.org/10.3390/molecules18043962
Chicago/Turabian StyleLe Lamer, Anne-Cécile, Nehal Ibrahim, Frédéric Manjary, Sonia Mallet-Ladeira, Cynthia Girardi, Alexis Valentin, Nicolas Fabre, and Claude Moulis. 2013. "Macrocyclic Spermidine Alkaloids from Androya decaryi L. Perrier" Molecules 18, no. 4: 3962-3971. https://doi.org/10.3390/molecules18043962