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Rare Syringyl Acylated Flavonol Glycosides from the Aerial Parts of Leonurus japonicus Houtt.
Tianjin State Key Laboratory of Modern Chinese Medicine, 312 Anshanxi Road, Nankai District, Tianjin 300193, China
Tianjin Key Laboratory of TCM Chemistry and Analysis, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 312 Anshan Road, Nankai District, Tianjin 300193, China
* Author to whom correspondence should be addressed.
Received: 4 February 2013; in revised form: 24 February 2013 / Accepted: 26 February 2013 / Published: 4 March 2013
Abstract: Five new syringyl acylated flavonol glycosides, named leonurusoides A (1), B (2), C (3), D (4), and E (5), together with one known one 6 were obtained from the aerial parts of Leonurus japonicus. Their structures were elucidated by chemical and spectroscopic methods (UV, IR, HRESI-TOF-MS, 1D and 2D NMR). Compounds 1-6 showed triglyceride (TG) accumulation inhibitory effects in free fatty acid-induced HepG2 cells.
Keywords: Leonurus japonicus; syringyl acylated flavonol glycosides; TG accumulation inhibitory effects; HepG2 cells
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Zhang, Y.; Deng, S.; Qu, L.; An, Y.-T.; Wu, C.-H.; Han, L.-F.; Gao, X.-M.; Wang, T. Rare Syringyl Acylated Flavonol Glycosides from the Aerial Parts of Leonurus japonicus Houtt.. Molecules 2013, 18, 2967-2977.
Zhang Y, Deng S, Qu L, An Y-T, Wu C-H, Han L-F, Gao X-M, Wang T. Rare Syringyl Acylated Flavonol Glycosides from the Aerial Parts of Leonurus japonicus Houtt.. Molecules. 2013; 18(3):2967-2977.
Zhang, Yi; Deng, Shen; Qu, Lu; An, Ya-Ting; Wu, Chun-Hua; Han, Li-Feng; Gao, Xiu-Mei; Wang, Tao. 2013. "Rare Syringyl Acylated Flavonol Glycosides from the Aerial Parts of Leonurus japonicus Houtt.." Molecules 18, no. 3: 2967-2977.