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Molecules 2013, 18(3), 2967-2977; doi:10.3390/molecules18032967
Article

Rare Syringyl Acylated Flavonol Glycosides from the Aerial Parts of Leonurus japonicus Houtt.

1, 2, 2, 2, 2, 2, 1,2 and 1,2,*
Received: 4 February 2013 / Revised: 24 February 2013 / Accepted: 26 February 2013 / Published: 4 March 2013
(This article belongs to the Section Metabolites)
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Abstract

Five new syringyl acylated flavonol glycosides, named leonurusoides A (1), B (2), C (3), D (4), and E (5), together with one known one 6 were obtained from the aerial parts of Leonurus japonicus. Their structures were elucidated by chemical and spectroscopic methods (UV, IR, HRESI-TOF-MS, 1D and 2D NMR). Compounds 1-6 showed triglyceride (TG) accumulation inhibitory effects in free fatty acid-induced HepG2 cells.
Keywords: Leonurus japonicus; syringyl acylated flavonol glycosides; TG accumulation inhibitory effects; HepG2 cells Leonurus japonicus; syringyl acylated flavonol glycosides; TG accumulation inhibitory effects; HepG2 cells
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Zhang, Y.; Deng, S.; Qu, L.; An, Y.-T.; Wu, C.-H.; Han, L.-F.; Gao, X.-M.; Wang, T. Rare Syringyl Acylated Flavonol Glycosides from the Aerial Parts of Leonurus japonicus Houtt.. Molecules 2013, 18, 2967-2977.

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