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Molecules 2013, 18(3), 2967-2977; doi:10.3390/molecules18032967
Article

Rare Syringyl Acylated Flavonol Glycosides from the Aerial Parts of Leonurus japonicus Houtt.

1, 2, 2, 2, 2, 2, 1,2 and 1,2,*
1 Tianjin State Key Laboratory of Modern Chinese Medicine, 312 Anshanxi Road, Nankai District, Tianjin 300193, China 2 Tianjin Key Laboratory of TCM Chemistry and Analysis, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 312 Anshan Road, Nankai District, Tianjin 300193, China
* Author to whom correspondence should be addressed.
Received: 4 February 2013 / Revised: 24 February 2013 / Accepted: 26 February 2013 / Published: 4 March 2013
(This article belongs to the Section Natural Products)
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Abstract

Five new syringyl acylated flavonol glycosides, named leonurusoides A (1), B (2), C (3), D (4), and E (5), together with one known one 6 were obtained from the aerial parts of Leonurus japonicus. Their structures were elucidated by chemical and spectroscopic methods (UV, IR, HRESI-TOF-MS, 1D and 2D NMR). Compounds 1-6 showed triglyceride (TG) accumulation inhibitory effects in free fatty acid-induced HepG2 cells.
Keywords: Leonurus japonicus; syringyl acylated flavonol glycosides; TG accumulation inhibitory effects; HepG2 cells Leonurus japonicus; syringyl acylated flavonol glycosides; TG accumulation inhibitory effects; HepG2 cells
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Zhang, Y.; Deng, S.; Qu, L.; An, Y.-T.; Wu, C.-H.; Han, L.-F.; Gao, X.-M.; Wang, T. Rare Syringyl Acylated Flavonol Glycosides from the Aerial Parts of Leonurus japonicus Houtt.. Molecules 2013, 18, 2967-2977.

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