Molecules 2013, 18(3), 2895-2903; doi:10.3390/molecules18032895
Article

A New 5α,8α-Epidioxysterol from the Soft Coral Sinularia gaweli

1,2,†email, 3email, 3,†email, 4email, 1,2email, 1,2,5email, 2,5email, 1,2email, 2,6email, 2email, 5,6email, 5,6email, 5,6,* email and 1,2,5,7,* email
Received: 5 February 2013; in revised form: 27 February 2013 / Accepted: 28 February 2013 / Published: 4 March 2013
(This article belongs to the Section Natural Products)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: A new sterol, (22R,23R,24R)-5α,8α-epidioxy-22,23-methylene-24-methyl-cholest-6,9(11)-dien-3β-ol (1), and two known sterols, (22R,23R,24R)-5α,8α-epidioxy-22,23-methylene-24-methylcholest-6-en-3β-ol (2) and 24-methylenecholestane-1α,3β,5α, 6β,11α-pentol (3), were isolated from the soft coral Sinularia gaweli. The structure of sterol 1 was established by spectroscopic methods and by comparison of the spectral data with those of known analogues. The cytotoxicity of sterols 13 towards various tumor cells is reported.
Keywords: Sinularia; epidioxysterol; cytotoxicity
PDF Full-text Download PDF Full-Text [233 KB, Updated Version, uploaded 18 June 2014 20:03 CEST]
The original version is still available [226 KB, uploaded 18 June 2014 20:03 CEST]

Export to BibTeX |
EndNote


MDPI and ACS Style

Yen, W.-H.; Chen, W.-F.; Cheng, C.-H.; Dai, C.-F.; Lu, M.-C.; Su, J.-H.; Su, Y.-D.; Chen, Y.-H.; Chang, Y.-C.; Chen, Y.-H.; Sheu, J.-H.; Lin, C.-S.; Wen, Z.-H.; Sung, P.-J. A New 5α,8α-Epidioxysterol from the Soft Coral Sinularia gaweli. Molecules 2013, 18, 2895-2903.

AMA Style

Yen W-H, Chen W-F, Cheng C-H, Dai C-F, Lu M-C, Su J-H, Su Y-D, Chen Y-H, Chang Y-C, Chen Y-H, Sheu J-H, Lin C-S, Wen Z-H, Sung P-J. A New 5α,8α-Epidioxysterol from the Soft Coral Sinularia gaweli. Molecules. 2013; 18(3):2895-2903.

Chicago/Turabian Style

Yen, Wei-Hsuan; Chen, Wu-Fu; Cheng, Ching-Hsiao; Dai, Chang-Feng; Lu, Mei-Chin; Su, Jui-Hsin; Su, Yin-Di; Chen, Yu-Hsin; Chang, Yu-Chia; Chen, Yung-Husan; Sheu, Jyh-Horng; Lin, Chan-Shing; Wen, Zhi-Hong; Sung, Ping-Jyun. 2013. "A New 5α,8α-Epidioxysterol from the Soft Coral Sinularia gaweli." Molecules 18, no. 3: 2895-2903.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert