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Molecules 2013, 18(3), 2501-2517; doi:10.3390/molecules18032501
Article

Synthesis, Characterization and Microwave-Promoted Catalytic Activity of Novel N-phenylbenzimidazolium Salts in Heck-Mizoroki and Suzuki-Miyaura Cross-Coupling Reactions under Mild Conditions

1
, 2,* , 3
 and 4
1 Battalgazi Vocational School, İnönü University, Battalgazi, 44210 Malatya, Turkey 2 Department of Chemistry, Faculty of Science, İnönü University, 44280 Malatya, Turkey 3 Department of Elementary Education, Faculty of Education, Hakkari University, 30000 Hakkari, Turkey 4 Department of Elementary Education, Faculty of Education, Adıyaman University, 02040 Adıyaman, Turkey
* Author to whom correspondence should be addressed.
Received: 25 December 2012 / Revised: 29 January 2013 / Accepted: 16 February 2013 / Published: 25 February 2013
(This article belongs to the Section Organic Synthesis)
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Abstract

A number of novel benzimidazolium salts having aryl substituents such as N-phenyl, 4-chlorophenyl and various alkyl substituents were synthesized. Their microwave-assisted catalytic activities were evaluated in Heck-Mizoroki and Suzuki-Miyaura cross-coupling reactions using a catalytic system consisting of Pd(OAc)2/K2CO3 in DMF/H2O under mild reaction conditions with consistent high yields, except those of 2-bromopyridine.
Keywords: N-phenylbenzimidazoles; Suzuki-Miyaura reaction; Heck-Mizoroki reaction; microwaves; NHC-precursor N-phenylbenzimidazoles; Suzuki-Miyaura reaction; Heck-Mizoroki reaction; microwaves; NHC-precursor
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Yılmaz, Ü.; Küçükbay, H.; Deniz, S.; Şireci, N. Synthesis, Characterization and Microwave-Promoted Catalytic Activity of Novel N-phenylbenzimidazolium Salts in Heck-Mizoroki and Suzuki-Miyaura Cross-Coupling Reactions under Mild Conditions. Molecules 2013, 18, 2501-2517.

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