Molecules 2013, 18(12), 15126-15133; doi:10.3390/molecules181215126
Article

Polyketides from the Halotolerant Fungus Myrothecium sp. GS-17

1,* email, 2email, 3email, 3email, 3email, 4email, 5email, 3email and 3email
Received: 12 November 2013; in revised form: 29 November 2013 / Accepted: 4 December 2013 / Published: 6 December 2013
(This article belongs to the Section Natural Products)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Two new polyketides, myrothecol (1) and 5-hydroxy-3-methyl-4-(1- hydroxylethyl)-furan-2(5H)-one (2), were isolated from the fermentation broth of the halotolerant fungus Myrothecium sp. GS-17 along with three known compounds, 5-hydroxyl-3-[(1S)-1-hydroxyethyl]-4-methylfuran-2(5H)-one (3), 3,5-dimethyl-4- hydroxylmethyl-5-methoxyfuran-2(5H)-one (4), and 3,5-dimethyl-4-hydroxymethyl-5- hydroxyfuran-2(5H)-one (5). Compound 1 is the first natural occurring polyketide with a unique furylisobenzofuran skeleton. The structures of these compounds were established via extensive spectroscopic analyses including 1D-, 2D-NMR, HRESI-MS, and crystal X-ray diffraction analysis.
Keywords: halotolerant fungus; Myrothecium sp.; polyketide; furanone
PDF Full-text Download PDF Full-Text [436 KB, uploaded 18 June 2014 20:16 CEST]

Export to BibTeX |
EndNote


MDPI and ACS Style

Liu, T.; Zhu, J.; Zhang, S.-Y.; Li, Z.-L.; Guan, L.-P.; Pan, H.-Q.; Wu, X.; Bai, J.; Hua, H.-M. Polyketides from the Halotolerant Fungus Myrothecium sp. GS-17. Molecules 2013, 18, 15126-15133.

AMA Style

Liu T, Zhu J, Zhang S-Y, Li Z-L, Guan L-P, Pan H-Q, Wu X, Bai J, Hua H-M. Polyketides from the Halotolerant Fungus Myrothecium sp. GS-17. Molecules. 2013; 18(12):15126-15133.

Chicago/Turabian Style

Liu, Tao; Zhu, Jing; Zhang, Song-Ya; Li, Zhan-Lin; Guan, Li-Ping; Pan, Hua-Qi; Wu, Xin; Bai, Jiao; Hua, Hui-Ming. 2013. "Polyketides from the Halotolerant Fungus Myrothecium sp. GS-17." Molecules 18, no. 12: 15126-15133.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert