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Polyketides from the Halotolerant Fungus Myrothecium sp. GS-17
AbstractTwo new polyketides, myrothecol (1) and 5-hydroxy-3-methyl-4-(1- hydroxylethyl)-furan-2(5H)-one (2), were isolated from the fermentation broth of the halotolerant fungus Myrothecium sp. GS-17 along with three known compounds, 5-hydroxyl-3-[(1S)-1-hydroxyethyl]-4-methylfuran-2(5H)-one (3), 3,5-dimethyl-4- hydroxylmethyl-5-methoxyfuran-2(5H)-one (4), and 3,5-dimethyl-4-hydroxymethyl-5- hydroxyfuran-2(5H)-one (5). Compound 1 is the first natural occurring polyketide with a unique furylisobenzofuran skeleton. The structures of these compounds were established via extensive spectroscopic analyses including 1D-, 2D-NMR, HRESI-MS, and crystal X-ray diffraction analysis.
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Liu, T.; Zhu, J.; Zhang, S.-Y.; Li, Z.-L.; Guan, L.-P.; Pan, H.-Q.; Wu, X.; Bai, J.; Hua, H.-M. Polyketides from the Halotolerant Fungus Myrothecium sp. GS-17. Molecules 2013, 18, 15126-15133.View more citation formats
Liu T, Zhu J, Zhang S-Y, Li Z-L, Guan L-P, Pan H-Q, Wu X, Bai J, Hua H-M. Polyketides from the Halotolerant Fungus Myrothecium sp. GS-17. Molecules. 2013; 18(12):15126-15133.Chicago/Turabian Style
Liu, Tao; Zhu, Jing; Zhang, Song-Ya; Li, Zhan-Lin; Guan, Li-Ping; Pan, Hua-Qi; Wu, Xin; Bai, Jiao; Hua, Hui-Ming. 2013. "Polyketides from the Halotolerant Fungus Myrothecium sp. GS-17." Molecules 18, no. 12: 15126-15133.