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Molecules 2013, 18(11), 13910-13919; doi:10.3390/molecules181113910

The Henry Reaction in [Bmim][PF6]-based Microemulsions Promoted by Acylase

* ,
School of Chemistry, Biology and Material Science, East China Institute of Technology, Nanchang 330013, China
* Authors to whom correspondence should be addressed.
Received: 21 October 2013 / Revised: 4 November 2013 / Accepted: 5 November 2013 / Published: 11 November 2013
(This article belongs to the Section Organic Synthesis)
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An environmentally-friendly, enzyme-promoted procedure for the Henry reaction was first studied using water-in-[Bmim][PF6] microemulsions as reaction medium. The Amano acylase from Aspergillus oryzae showed better catalytic activity for the addition reactions of nitromethane with a series of aromatic aldehydes, and a highest yield of 90% was obtained.
Keywords: Henry reaction; acylase; water-in-[Bmim][PF6] microemulsion; enzyme promiscuity Henry reaction; acylase; water-in-[Bmim][PF6] microemulsion; enzyme promiscuity
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Xia, W.-J.; Xie, Z.-B.; Jiang, G.-F.; Le, Z.-G. The Henry Reaction in [Bmim][PF6]-based Microemulsions Promoted by Acylase. Molecules 2013, 18, 13910-13919.

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